Congenital Heart Disease: Causes & Reasons

Possible Causes for Congenital Heart Disease

Most infants with trisomy 13 have congenital heart disease. [nlm.nih.gov]

heart disease, blindness, severe mental retardation may complicate survival Please rate topic. [medbullets.com]

There are often signs of congenital heart disease, such as: Abnormal placement of the heart toward the right side of the chest instead of the left Atrial septal defect Patent [nlm.nih.gov]

Primary Pulmonary Arterial Hypertension

Disease, Pulmonary Hypertension due to Lung Disease and/or Hypoxia, Pulmonary Arterial Hypertension Associated with Congenital Heart Disease, World Health Organization Group [books.google.com]

Pulmonary Hypertension Related to Congenital Heart Disease: Congenital heart diseases are those that are present at birth and involve abnormalities with the structure of the [pulmonaryhypertensionrn.com]

However, PAH associated with congenital heart disease has a better prognosis than idiopathic PAH. [patient.info]

Aortic Valve Stenosis

Patients were excluded if they had an ejection fraction <40%, other significant valvular or congenital heart disease, end-stage renal disease or heart transplant. [ncbi.nlm.nih.gov]

In Japan, some adult congenital heart disease (ACHD) patients continue to be followed by pediatric cardiologists, though the patterns of practice are variable. [ncbi.nlm.nih.gov]

Cyanotic Congenital Heart Disease

Four patients, 27 to 47 years of age, with cyanotic congenital heart disease were enrolled from the Outpatient Clinic of the Ahmanson/UCLA Adult Congenital Heart Disease Center [ncbi.nlm.nih.gov]

Mesangiolysis associated with glomerulomegaly was observed in an autopsy case of an 11-year-old boy with cyanotic congenital heart disease, i.e. complete transposition of [ncbi.nlm.nih.gov]

A total of 38 matched acyanotic patients with congenital heart disease served as controls. [ncbi.nlm.nih.gov]

Acyanotic Congenital Heart Disease

[…] cyanotic congenital heart disease (6). [acronyms.thefreedictionary.com]

Neuropsychological and behavioral status of Chinese children with acyanotic congenital heart disease. [acronymfinder.com]

"TABLE 7.12: ACYANOTIC CONGENITAL HEART DISEASE." Harriet Lane Handbook, 21st ed., Elsevier, 2018. [unboundmedicine.com]

Sick Sinus Syndrome

The objective of our study was to evaluate the clinical outcome of patients with operated congenital heart disease (CHD), post-operative sinus node dysfunction and atrial [ncbi.nlm.nih.gov]

Abstract Aims The objective of our study was to evaluate the clinical outcome of patients with operated congenital heart disease (CHD), post-operative sinus node dysfunction [doi.org]

It may be isolated or associated with other congenital heart diseases. [ncbi.nlm.nih.gov]

Noonan Syndrome

The challenges faced during anesthetic management of patients with NS could be due to congenital heart diseases, hemostatic disorders, and airway anomalies. [ncbi.nlm.nih.gov]

heart disease, and other comorbidities. [pediatrics.aappublications.org]

Researchers find new drug compound that treats laboratory mice with congenital heart disease Congenital heart disease is the most common form of birth defect, affecting one [news-medical.net]

Holt-Oram Syndrome

This review summarizes recent developments in the study of TBX5 as it relates to congenital heart disease and the pathology of HOS. [ncbi.nlm.nih.gov]

Information Authors Mutations in the T-box transcription factor TBX5 cause Holt-Oram syndrome (HOS), an autosomal-dominant condition characterized by a familial history of congenital [journals.lww.com]

Syndromes Associated with Congenital Heart Disease DiGeorge Syndrome Interrupted aortic arch Down’s syndrome (Trisomy 21) Endocardial cushion defect (25%) Membranous VSD ASD–ostium [learningradiology.com]

Trisomy 18

A prenatal diagnosis of ductal-dependent, complex congenital heart disease was made in a fetus with trisomy 18. [ncbi.nlm.nih.gov]

METHODS: A retrospective chart review of patients with trisomy 18 and congenital heart disease from 2005 to 2017 was performed. [ncbi.nlm.nih.gov]

Abstract A prenatal diagnosis of ductal-dependent, complex congenital heart disease was made in a fetus with trisomy 18. [pediatrics.aappublications.org]

DiGeorge Syndrome

CATCH 22 is the mnemonic to remember the chromosome and all the abnormalities. cleft lip +/- palate congenital heart disease (particularly conotruncal anomalies ): often a [radiopaedia.org]

Next to Down syndrome, DiGeorge syndrome is the most common genetic cause of congenital heart disease. [medicinenet.com]

DiGeorge syndrome: A genetic disorder characterized by hypocalcemia, immunodeficiency, and congenital heart disease : Hypocalcemia (low calcium levels in the blood) due to [medicinenet.com]

Thymic Aplasia

The diagnosis of DiGeorge syndrome was made in each on the basis of refractory hypocalcemia, typical facial features, absent thymic shadow, congenital heart disease and repeatedly [nature.com]

It is also associated with abnormalities of the parathyroid glands and with consequent hypo-calcemic tetany and congenital heart disease. [btb.termiumplus.gc.ca]

Commonly associated signs and symptoms include: Congenital heart disease It is found in around 40 % of the individuals. [lecturio.com]

Trisomy 21

heart disease and Down syndrome. [ncbi.nlm.nih.gov]

BACKGROUND: The pattern and risk factors for congenital heart diseases (CHD) in children with Down syndrome (DS) vary over time. [ncbi.nlm.nih.gov]

The prevalence of congenital heart disease in infants with Down syndrome is 40%, compared with 0.3% in children who have normal chromosomes. [ncbi.nlm.nih.gov]

Velocardiofacial Syndrome

Due to clinical suspicion it was requested in 2 boys and one girl with congenital conotruncal heart disease. [scielo.sa.cr]

A highly variable syndrome of associated anomalies including congenital heart disease, dysmorphic features, palate anomalies, and some degree of learning disabilities or mental [en.wikibooks.org]

We report on a child with congenital heart disease (atrial septal defect, ventricular septal defect, pulmonic stenosis), submucosal cleft palate, hypernasal speech, learning [ncbi.nlm.nih.gov]

Turner Syndrome

KEYWORDS: Turner syndrome; congenital heart disease; outcomes; trisomy 21 [ncbi.nlm.nih.gov]

Results were compared with previously published results of this questionnaire in women with congenital heart disease. [ncbi.nlm.nih.gov]

Congenital heart disease, hypertension, aortic dilation and 45,X are predisposing factors. [internetmedicin.se]

CHARGE Syndrome

Alternative tests to consider The Invitae Isolated and Syndromic Congenital Heart Disease Panel has been designed to provide a broad genetic analysis of congenital heart disease [invitae.com]

heart disease tetralogy of Fallot atrioventricular canal defect double outlet right ventricle short stature cleft palate +/- lip esophageal atresia / tracheo-esophageal fistula [radiopaedia.org]

Coloboma, congenital heart disease, and choanal atresia with multiple anomalies: CHARGE association. J Pediatr. 1981 Aug. 99(2):223-7. [Medline]. Pampal A. [emedicine.medscape.com]

Ellis-Van Creveld Syndrome

In 1940 Ellis and van Creveld (2) described 2 more patients with similar congenital anomalies who, in addition, had congenital heart disease. [annals.org]

What to Watch for With Ellis-van Creveld Syndrome Congenital heart disease is common; therefore cardiologist consultation is strongly recommended at diagnosis. [nemours.org]

Keywords: Clinical features; Congenital heart disease; Syndrome Case Presentation A 27-year-old female, was referred for evaluation of shortness of breath on exertion of 1 [austinpublishinggroup.com]

Wolf-Hirschhorn Syndrome

heart disease. [ncbi.nlm.nih.gov]

Associated congenital anomalies include midline fusion defects (cleft lip/palate, hypospadias), renal anomalies such as dysplastic kidney (23%), congenital heart disease [mjdrdypu.org]

Congenital heart disease associated with WHS typically includes atrial and ventricular septal defects, though there are a few case reports of associated complex congenital [ncbi.nlm.nih.gov]

Duodenal Atresia

Heart Disease Nomenclature and Classification 665 Palliative Procedures 668 Congenital Heart Disease LefttoRight Shunt Lesions 672 Congenital Heart Disease Cyanotic Lesions [books.google.com]

All four patients underwent successful surgery but one infant with Down's syndrome subsequently died of congenital heart disease. [ncbi.nlm.nih.gov]

Congenital heart disease in patients with trisomy 21 and duodenal atresia is well known. [ncbi.nlm.nih.gov]

Cornelia De Lange Syndrome

Congenital heart disease (CHD) is not a major criterion of the disease, but it affects many individuals. [ncbi.nlm.nih.gov]

heart disease. [emedicine.medscape.com]

By using intrauterine growth retardation as a trigger for antenatal diagnosis, CdLS is diagnosed by abnormalities of upper arms, congenital heart diseases, and characteristic [hindawi.com]

Laurence Moon Syndrome

heart disease. [jamanetwork.com]

Other complications of the disease include diabetes mellitus, renal abnormalities, psychiatric illness, developmental delay, abnormal facies, and congenital heart disease, [cags.org.ae]

Congenital heart disease 10. Hepatic fibrosis Treatment[edit] There is no cure to LNMS. However, symptomatic treatment is often provided. [en.wikipedia.org]

Thrombocytopenia-Absent Radius Syndrome

heart disease (eg. [symptoma.com]

Other frequent associations are congenital heart disease and a high incidence of cow's milk intolerance. [ncbi.nlm.nih.gov]

Congenital heart disease, principally tetralogy of Fallot and septal defects, is present in one-third of cases [2]. [degruyter.com]

Kartagener Syndrome

We classified 3 patients with SI and congenital heart disease as heterotaxy, because these patients did not have mirror image reversal of situs solitus. [doi.org]

An uncommon anomaly that accounts for less than 1% of all congenital heart diseases, CTGA occurs in a typical criss-cross pattern (S, L, L). [revespcardiol.org]

Heterotaxy syndrome: asplenia and polysplenia as indicators of visceral malposition and complex congenital heart disease. Biol Neonate. 2005 ; 88 : 278–290. [doi.org]

Smith Lemli Opitz Syndrome

Chest radiography is important in looking for congenital heart disease and/or congenital pulmonary abnormalities. [patient.info]

The malformations present were facial dysmorphisms, cleft palate, congenital heart disease, genitourinary abnormalities, and syndactyly of the toes. [ncbi.nlm.nih.gov]

Congenital heart disease consisted of hypoplastic left heart, coronary sinus agenesis, ostium secundum and ostium primum defects, and a thickened septum primum. [ncbi.nlm.nih.gov]

Marfan Syndrome

The Ahmanson/UCLA Adult Congenital Heart Disease Center manages all forms of congenital heart disease. We are a "Marfan Clinic" as designated by the Marfan Foundation. [uclahealth.org]

UAB’s Alabama Adult Congenital Heart Disease Program is designed to prevent that gap in care. [uabmedicine.org]

A blood test to check for the abnormal gene More information on Marfan Syndrome For an appointment, please call: UCLA-Adult Congenital Heart Disease Center 100 Medical Plaza [uclahealth.org]

Cri Du Chat Syndrome

heart disease (CHD) found in this population, to review the literature for previously published accounts of CHD in this population, and to review current genotype-phenotype [ncbi.nlm.nih.gov]

To analyze the cases submitted to the Pediatric Cardiac Care Consortium (PCCC) database from 1982 to 2002 to determine the frequency and distribution of congenital heart disease [pediatrics.aappublications.org]

heart disease (CHD). [journalmc.org]

Kabuki Syndrome

Kabuki-Syndrome and Congenital Heart Disease—A Twenty-Year Institutional Experience. Congenital Heart Disease, 16(2), 171–181. [techscience.com]

The syndrome is characterized by the following clinical features: Short stature Developmental delay Congenital heart disease Skeletal anomalies Cleft Palate Distinct facial [immunodeficiencysearch.com]

As congenital heart diseases are often present, cardiac ultrasonography is a useful study. [symptoma.com]

Rubinstein-Taybi Syndrome

heart disease. [symptoma.com]

Major causes of morbidity and mortality in the first years of life include the following: Respiratory infections Complications from congenital heart disease Instability of [emedicine.com]

[…] of accompanying findings, such as congenital heart disease, recurrent respiratory infections, and cryptorchidism. [symptoma.com]

Rheumatic Heart Disease

Most of the reported cases of calcified pulmonary valves are associated with congenital heart disease. [ncbi.nlm.nih.gov]

Six patients presented with a combination of RHD and congenital heart disease. [ncbi.nlm.nih.gov]

We report the first case of C. striatum endocarditis in a patient with congenital lymphedema and rheumatic heart disease. [ncbi.nlm.nih.gov]

Partial Monosomy 18q

The symptoms are palatal abnormalities, congenital heart disease, facial dysmorphia, microcephaly, hypocalcemia and thymic hypoplasia with T-cell imunity defect. [wikilectures.eu]

Associated syndromes: congenital heart disease, leukemia, premature Alzheimer's disease (same morphological changes). [kumc.edu]

Children with Downs syndrome often have cyanotic congenital heart disease. [academic.oup.com]

Williams-Beuren Syndrome

Williams syndrome, initially described by Williams, Barratt-Boyes, and Lowe in 1961, consists of characteristic dysmorphic features, congenital heart disease, and distinctive [ncbi.nlm.nih.gov]

Patients with aortic valve stenosis or regurgitation, unoperated congenital heart disease, or history of aortic dissection or replacement, were excluded. [isachd.connectedcommunity.org]

We report a toddler with Williams syndrome (WS) complicated by congenital heart disease and a seizure-like episode who died suddenly several hours after uneventful cardiac [ncbi.nlm.nih.gov]