Cognitive Impairment: Causes & Reasons

Possible Causes for Cognitive Impairment

use of a combination of education, skills training on self-management strategies and cognitive exercises for the clinical rehabilitation management of cognitive impairment [who.int]

[…] strategies, such as nasal breathing and pacing approaches and, in the absence of PESE, physical exercise training for the clinical rehabilitation management of breathing impairment [who.int]

Alzheimer Disease

Review Summary: Depression is highly prevalent in mild cognitive impairment and most dementias. [oadoi.org]

It is important to detect and effectively treat depression because the comorbidity of depression and cognitive impairment is associated with greater cognitive and functional [oadoi.org]

Pharmacologic and nonpharmacologic treatment approaches are both efficacious in reducing depression in cognitive impairment and dementia. [oadoi.org]

Alcohol Dementia

Adults age 72 and older with mild cognitive impairment (MCI) who drank more than 14 alcoholic drinks a week were 72% more likely to progress to dementia over an eight-year [hsph.harvard.edu]

Completely abstaining from alcohol among those without mild cognitive impairment, and consuming more than 14 alcoholic drinks each week among those with mild cognitive impairment [healio.com]

‘Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment’ by Manja Koch et al. was published in JAMA Network [sciencemediacentre.org]

Late-Onset Depression

In all, 28 (53.8%) were found to have cognitive impairment at baseline and 8 (28.6%) of them had improvement after 6 months. [ncbi.nlm.nih.gov]

Keywords: Depression, cognitive impairment, elderly, vascular risk, neurologic diseases, framingham risk score. [eurekaselect.com]

Abstract To identify the association between the functional and structural changes of default mode network (DMN) underlying the cognitive impairment in Late-onset depression [ncbi.nlm.nih.gov]

Dementia

Clinicians can diagnose the syndromes of dementia (major neurocognitive disorder) and mild cognitive impairment (mild neurocognitive disorder) based on history, examination [ncbi.nlm.nih.gov]

Mild cognitive impairment (MCI) is defined as the symptomatic predementia stage on the continuum of cognitive decline, characterized by objective impairment in cognition that [doi.org]

A review of screening tests for cognitive impairment Breda Cullen 1, Brian O’Neill 1, Jonathan J Evans 2, Robert F Coen 3, Brian A Lawlor 3 1 Department of Neuropsychology [doi.org]

Traumatic Brain Injury

There are no FDA-approved treatments for ECT-induced cognitive impairments or for cognitive impairments in neurologic and psychiatric disorders except AD. [ncbi.nlm.nih.gov]

[…] the relationship between subjective reports of cognitive impairments and TBI participants' performances on cognitive tests. [doi.org]

Galantamine and memantine have shown efficacy for the treatment of ECT- and TBI-induced cognitive impairments. [ncbi.nlm.nih.gov]

Primary Progressive Multiple Sclerosis

[…] and T2LL and specific cognitive impairments suggests that models that predict cognitive impairment in PPMS should include comprehensive MRI assessments of both GM and WM. [ncbi.nlm.nih.gov]

RESULTS: Twenty-nine percent of patients were categorized as cognitively impaired. [ncbi.nlm.nih.gov]

impairment is common in PPMS and affects all evaluated cognitive domains. [ncbi.nlm.nih.gov]

Multi-Infarct Dementia

As far as the cognitive impairment is concerned, there is no pathognomonic radiological lesion. [doi.org]

Table 3 Evaluation of cognitive impairment, GDS and GSS for study participants Characteristics Division F or χ2 (P) Post-hoc Total AD group (a) VD group (b) Normal (c) K-MMSE [kjcls.org]

Abstract Peripheral blood mononuclear cells (PBMC) from 40 consecutive patients entering a screening program on cognitive impairment were studied in vitro with respect to [ncbi.nlm.nih.gov]

Dialysis Dementia

Several studies that examined the prevalence of cognitive impairment assessed by neuropsychological tests among ESRD patients indicate that the prevalence of cognitive impairment [bmcnephrol.biomedcentral.com]

Mild cognitive impairment is considered to be a transitional phase between normal cognitive function and dementia. [kidney.org]

Cognitive impairment in the aging dialysis and chronic kidney disease populations: An occult burden. [awakeningfromalzheimers.com]

Binswanger Disease

cognitive impairment. [medlink.com]

Lars-Olof Wahlund, Timo Erkinjuntti, Serge Gauthier Cambridge University Press, 12 feb. 2009 - 241 páginas Vascular cognitive impairment is the second most common cause of [books.google.es]

VCI, vascular cognitive impairment, not yet dementia. [academic.oup.com]

Normal Pressure Hydrocephalus

In our study, we investigated the impact of cognitive impairment on gait improvement after STT. [ncbi.nlm.nih.gov]

Cognitive impairments were the most common symptoms (n = 6) followed by gait disturbances (n = 3); however, urinary incontinence was not observed. [ncbi.nlm.nih.gov]

There were significant correlations between swallowing impairment and gait disturbance (r = 0.358, p = 0.009), and RST and cognitive impairment (r = -0.502, p < 0.001). [ncbi.nlm.nih.gov]

Postconcussive Syndrome

Abstract The purpose of the present study is to identify otherwise occult white matter abnormalities in patients suffering persistent cognitive impairment due to mild traumatic [doi.org]

Traumatic brain injury (TBI) may result in a variety of cognitive, behavioural and physical impairments. [doi.org]

impairment. [ncbi.nlm.nih.gov]

Organic Brain Syndrome

Longer treatment periods and further specifications with regard to the aetiopathology and degree of cognitive impairment are recommended for further clinical studies of this [ncbi.nlm.nih.gov]

In OBS patients with a mild to moderate degree of cognitive impairment, oxiracetam showed to improve cognitive functions, logical performance, and attention. [ncbi.nlm.nih.gov]

Reliability of the D scale was significantly lower when the subjects interviewed scored highly on the OBS scale (severe cognitive impairment). [ncbi.nlm.nih.gov]

Hepatic Encephalopathy

There is a progressive reduction in rs-FC in the default mode network with the progression of cognitive impairment. [ncbi.nlm.nih.gov]

RESULTS: Compared with control subjects, the patients with cirrhosis had lower psychometric HE scores, indicating cognitive impairments. [ncbi.nlm.nih.gov]

The demonstration of MHE is done through neuropsychological testing in the absence of clinical evidence of HE, patients showing only a mild cognitive impairment. [ncbi.nlm.nih.gov]

Alcoholic Amnestic Disorder

George, O, Sanders, C, Freiling, J et al ( 2012 ) Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol [apt.rcpsych.org]

Prevalence and classification of mild cognitive impairment in theCardiovascular Health Study Cognition Study: part 1. Arch Neurol2003;60(10):1385–1389. [link.springer.com]

[…] of recent memory and disturbance of time sense in the absence of impaired immediate recall or generalized cognitive impairment. [alzres.biomedcentral.com]

Dementia with Lewy Bodies

Vascular contributions to cognitive impairment and dementia (VCID) are conditions arising from stroke and other vascular brain injuries that cause significant changes to memory [nia.nih.gov]

CONCLUSION: This preliminary study suggests the existence of a potential « insular cognitive impairment » profile in DLB at the early stage. [ncbi.nlm.nih.gov]

impairment (MCI) with impairments in amnestic or nonamnestic cognitive domains. [ncbi.nlm.nih.gov]

Sepsis-Associated Encephalopathy

impairment at 1 year cognitive impairment may persist for years up to 58% of sepsis survivors have long-term symptoms of depression and/or anxiety delirium is associated [lifeinthefastlane.com]

Moreover, sepsis survivors can suffer from long-term cognitive impairments that impact their quality of life. [clinicaltrials.gov]

It is characterized as an acute impairment of cognition, with a fluctuating course, impaired attention, and altered level of consciousness. [alvinandassociateslnc.com]

Neurodegenerative Disorder

’s disease (PD), vascular cognitive impairment (VCI), frontotemporal dementia (FTD), and amyotrophic lateral sclerosis (ALS). [braininstitute.ca]

Emerging diagnoses (37.4%) were dementia with Lewy bodies (DLB) in 29 subjects, Parkinson disease (PD) in 22, multiple system atrophy (MSA) in two, and mild cognitive impairment [ncbi.nlm.nih.gov]

impairment. [braininstitute.ca]

Boxer's Dementia

impairment. [medical-dictionary.thefreedictionary.com]

Dementia pugilistica (DP) is a form of chronic traumatic encephalopathy (CTE) that involves gross impairment of cognitive and motor functioning due to repetitive blows to [connect.springerpub.com]

impairments with reaction time, processing speed, and memory. [menshealth.com]

Drug-Induced Dementia

Drugs that can cause cognitive impairment Drug-induced cognitive impairment is most commonly linked to benzodiazepines, opiates, tricyclic antidepressants and anticonvulsants [worstpills.org]

See ASHA’s Mild Cognitive Impairment Evidence Map for summaries of the available evidence on this topic. [asha.org]

People already suffering from some cognitive impairment are most susceptible." [commondreams.org]

Metabolic Encephalopathy

Among 62 patients, we identified 10 patients with clinically significant cognitive impairment. [ncbi.nlm.nih.gov]

The clinical presentation of toxic leukoencephalopathy is extremely variable, ranging from minor cognitive impairment, easily confused with psychiatric illnesses, to severe [radiopaedia.org]

Macrophages secrete neurotoxic factors that elicit neuronal injury and inevitably death leading to the constellation of cognitive and motor impairments common during progressive [nebraska.pure.elsevier.com]

AIDS Dementia Complex

Abstract The AIDS dementia complex (ADC, also referred to as HIV-associated cognitive impairment) is a common disorder among HIV-infected patients associated with both inflammatory [ncbi.nlm.nih.gov]

Their density increased with increasing cognitive impairment and in parallel to the astrogliosis in the frontal cortex, basal ganglia and deep white matter. [ncbi.nlm.nih.gov]

Cognitive Impairments Cognitive impairments associated with HIV occur in the domains of attention, memory, verbal fluency, and visuospatial construction. [wikidoc.org]

Spinocerebellar ataxia Type 19/22

Overview Spinocerebellar ataxia 19: A rare genetic disorder (chromosome 1p21-q21 defect) characterized by mild cognitive impairment and myoclonus. [checkorphan.org]

It is possible that the cognitive impairment of the mother is due to the coincidental occurrence of dementia, as the proband did not show cognitive impairment. [journals.plos.org]

Cognitive impairments in cerebellar degeneration: a comparison with Huntington's disease. [demneuropsy.com.br]

Huntington Disease

Interventions designed to improve mobility and decrease fall risk should also address issues of cognitive impairments with particular consideration given to interventions [ncbi.nlm.nih.gov]

Cognitive impairment is a frequent clinical feature caused by different dementia subtypes. [ncbi.nlm.nih.gov]

This is especially true in Huntington's disease, where cognitive impairment is prominent. [ncbi.nlm.nih.gov]

Autosomal Dominant Spastic Paraplegia Type 10

Abstract Objective: To investigate the progression of cognitive impairment and its behavioral aspects in patients with SPG4-linked autosomal dominant hereditary spastic paraplegia [neurology.org]

SPG26 Gene unknown 12p11-q14 Unknown Child onset, complicated:distal amyotrophy cognitive impairment, dysarthria. [scielo.br]

(epilepsy), muscle atrophy, disturbance of the nerves in the arms and legs (neuropathy), and disturbance cognitive ability (intellectual impairment and dementia). [rarediseases.org]

Cerebrotendinous Xanthomatosis

impairments. [ncbi.nlm.nih.gov]

The main cause of disability results from neurologic manifestations including pyramidal signs, ataxia, and cognitive impairment. [ncbi.nlm.nih.gov]

impairment, intellectual disability, and learning difficulties. [ncbi.nlm.nih.gov]

Encephalopathy

impairment. [ncbi.nlm.nih.gov]

In chronic hepatitis patients the cognitive impairments correlate with ICT and elevated liver enzymes. [epublications.vu.lt]

Holidays from apheresis lasting several weeks and/or reductions in maintenance apheresis frequency to once per-week resulted in re-expression of ataxia and cognitive impairments [ncbi.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 56

(epilepsy), muscle atrophy, disturbance of the nerves in the arms and legs (neuropathy), and disturbance cognitive ability (intellectual impairment and dementia). [rarediseases.org]

Coexisting mental retardation or cognitive impairment has often been described in these families. [jnnp.bmj.com]

In the case of both KCNA2 families, these additional features consisted of cognitive impairment, ataxia, and sensory-motor axonal demyelinating peripheral neuropathy in some [epilepsygenetics.net]

Multiple Sclerosis

Treatment for patients with MS and cognitive impairment should, therefore, include a DMD in combination with a pharmacological or perhaps non-pharmacological cognitive-enhancement [dx.doi.org]

Within each atrophy group, patients with cognitive impairment and preserved cognitive function were compared and regression analyses were performed to predict cognitive impairment [ncbi.nlm.nih.gov]

However, the methods used to diagnose cognitive impairment, and to assess the effect of treatment on function over time and need to be refined. [dx.doi.org]

Congenital Muscular Dystrophy with Integrin Alpha-7 Deficiency

Cognitive impairment ranging from intellectual disability to mild cognitive delay, structural brain and/or eye abnormalities, and seizures are found almost exclusively in [ncbi.nlm.nih.gov]

impairment ; Congenital muscular dystrophy ; Elevated serum creatine phosphokinase ; Fatty replacement of skeletal muscle ; Increased variability in muscle fiber diameter [mousephenotype.org]

27 June 2014 Abstract This form of congenital muscular dystrophy is characterized by neonatal hypotonia, proximal muscle weakness and atrophy, delayed motor development, cognitive [link.springer.com]