Multiple Pulmonary Nodules: Causes & Reasons

Possible Causes for Multiple Pulmonary Nodules

Lymphomatoid granulomatosis (LYG) is a rare lung disorder diagnosed by radiological imaging of multiple pulmonary nodules and occasionally induced by methotrexate (MTX) use [ncbi.nlm.nih.gov]

Chest X-ray images showed multiple pulmonary nodules. Transbronchial lung biopsy specimens showed lymphocytic infiltrates but no malignant cells. [ncbi.nlm.nih.gov]

Pulmonary LYG usually presents as multiple pulmonary nodules with rapid progression and excavation. [karger.com]

Cryptococcosis

pulmonary nodules or masses, which mimics primary or metastatic malignancy. [5], [9], [10] A large solitary cryptococcoma replacing the majority of a lobe, as seen in our [ccij-online.org]

[…] or multiple pulmonary nodules or masses, seen in 10 (83%) of the 12 patients. [ajronline.org]

RESULTS: The most common CT finding was pulmonary nodules ( n = 9). Multiple nodules ( n = 7) were more common than solitary nodules ( n = 2). [pubs.rsna.org]

Metastatic Renal Cell Carcinoma

Multiple pulmonary nodules as described. Figure 5. [scmr.org]

The patient was advised to consider a below-knee amputation to prevent further metastases, but ct imaging revealed multiple new bilateral pulmonary nodules. [current-oncology.com]

Pulmonary metastases are usually asymptomatic (90% of cases). On CT images, they manifest as multiple nodules (75.6% of cases) or solitary nodules (30.5% of cases) (24). [pubs.rsna.org]

Pulmonary Metastasis

We present a case of histoplasmosis with multiple pulmonary nodules in a patient with a history of melanoma. [ncbi.nlm.nih.gov]

She was examined for multiple pulmonary nodules mimicking pulmonary metastasis that were detected with chest radiography and computed tomography of the thorax. [ncbi.nlm.nih.gov]

Nodules  May be solitary or multiple.  Rounded nodules of variable sizes ranging from few millimeters to few centimeters with well-defined margin. 75 % - multiple pulmonary [slideshare.net]

Pulmonary Lymphomatoid Granulomatosis

This demonstrates the potential for diagnostic difficulty in a case presentation of multiple pulmonary nodules. [ncbi.nlm.nih.gov]

Pulmonary LYG usually presents as multiple pulmonary nodules with rapid progression and excavation. [karger.com]

A repeat CT scan showed the decreased size of the lung nodules. [ncbi.nlm.nih.gov]

Pulmonary Syphilis

All of these cases presented with multiple pulmonary nodules. [err.ersjournals.com]

Chest CT scan and 18 F-fluorodeoxyglucose (FDG) PET/CT showed multiple pulmonary nodules mimicking pulmonary hematogenous metastases. [oalib.com]

Clinical Infectious Diseases, Feb 2006 We report the case of a homosexual, HIV-positive man with typical secondary syphilis and multiple excavated pulmonary subpleural nodules [paperity.org]

Pulmonary Cryptococcosis

CONCLUSION: Pulmonary cryptococcosis should be considered in the differential diagnosis of solitary or multiple pulmonary nodules. [ncbi.nlm.nih.gov]

The most common radiographic abnormalities were multiple pulmonary nodules or masses, seen in 8 and 5 cases of patients respectively. 14 patients received specific therapy [ncbi.nlm.nih.gov]

The most frequent radiologic abnormalities on chest computed tomography (CT) scans were solitary or multiple pulmonary nodules, and masses or consolidations, and most lesions [ncbi.nlm.nih.gov]

Caplan Syndrome

nodules have been reported previously in the setting of Caplan’s syndrome in miners.1 In 2007, Srinivas et al8 reported a case with multiple calcified pulmonary nodules in [birpublications.org]

Axial CT chest showing multiple pulmonary nodules in the right upper lobe. [ncbi.nlm.nih.gov]

Years later after Caplan's publication, multiple cases with pulmonary nodules in miners with RA were reported. [wikidoc.org]

Pulmonary Mycobacterial Infection

These organisms are commonly recovered on sputum or bronchoscopic cultures obtained as part of an evaluation for an abnormal CT scan of the chest demonstrating multiple pulmonary [consultqd.clevelandclinic.org]

NTM pulmonary infection could be suspected in selected patients who have multiple pulmonary nodules combined with diffuse bronchiectasis on the HRCT scan. [thorax.bmj.com]

In some individuals, the disease will present as a single or multiple small masses in the lungs (single or multiple pulmonary nodules) or as hypersensitivity pneumonitis, [rarediseases.org]

Pulmonary Clear Cell Tumor

A chest CT revealed multiple pulmonary nodules bilaterally, the largest measuring 15 mm. [spandidos-publications.com]

MeSH Descriptor Source: MeSH 2019 deskriptory Main Heading mnohočetné plicní uzly English Heading Multiple Pulmonary Nodules See (Czech) mnohočetné plicní noduly [cze0037457 [medvik.cz]

Cryptogenic organizing pneumonia (formerly known as BOOP) may present with fever, malaise, and a single nodule or multiple pulmonary nodules that are indistinguishable from [pulmonologyadvisor.com]

Pulmonary Nocardiosis

[…] low attenuation areas with or without cavitation, multiple pulmonary nodules, pleural effusion, and chest wall extension. [ncbi.nlm.nih.gov]

The typical clinical findings are those of bilateral multiple pulmonary nodules in young or middle aged Caucasian women. [ncbi.nlm.nih.gov]

We report a case of pulmonary nocardiosis with bilateral multiple cavitary nodules in a HIV-negative 60-year-old man with nephrotic syndrome who was receiving corticosteroid [ncbi.nlm.nih.gov]

Kaposi Sarcoma of the Lung

Computed Tomography revealed multiple opacities and pulmonary nodules. Biopsy of the skin lesion confirmed Kaposi sarcoma. [austinpublishinggroup.com]

She underwent high-resolution chest computed tomography that showed new multiple subcentimeter pulmonary nodules, diffusely dispersed throughout both lungs ( Fig. 1 A). [archbronconeumol.org]

Chest x-ray showed multiple nodular opacities in both lung fields. Computed tomography of the chest revealed multiple diffuse opacities and pulmonary nodules (Figure 1). [austinpublishinggroup.com]

Lymphocytic Interstitial Pneumonia

To our knowledge this is the first report of pediatric pSS with lymphocytic interstitial pneumonia and multiple pulmonary nodules on chest radiograph. [ncbi.nlm.nih.gov]

pulmonary nodules (may be cavitary) Skin rash Central nervous system (CNS) disease Hypersensitivity Pneumonitis Appropriate antigen exposure Diffuse ground-glass opacities [radiologykey.com]

[…] adenopathy Hyaline vascular form: Nodes have intense contrast enhancement Lungs less likely to be abnormal (if abnormal may be due to co-existing LIP) Lymphomatoid Granulomatosis Multiple [radiologykey.com]

Extrapelvic Endometriosis

Objective We present a case report of symptomatic compression of the right sciatic nerve notch, secondary to piriformis muscle endometriosis, as well as a literature review. Material and methods We report the case of a 29-year-old woman with 2-year evolution of right chronic sciatica. During the first year,[…] [revistaneurocirugia.com]

Pulmonary Hyalinizing Granuloma

Figures Figure 1 Posteroanterior (A) and lateral (B) chest radiographs of multiple pulmonary nodules Figure 2 Computed tomography image of multiple bilateral pulmonary nodules [pubmed.ncbi.nlm.nih.gov]

Roentgenograms display multiple bilateral pulmonary nodules which may be cavitated. [semanticscholar.org]

CT Pulmonary hyalinizing granulomas can appear as well-marginated solitary or multiple nodules varying from a few millimeters to 15 cm in size. [radiopaedia.org]

Uterine Intravascular Leiomyomatosis

pulmonary nodules: a report of 2 cases, Medicine (Baltimore), № 95 https://doi.org/10.1097/MD.0000000000004722 Barnas, Natural history of leiomyomas beyond the uterus, Medicine [ouci.dntb.gov.ua]

Intravenous leiomyomatosis with inferior vena cava or intracardiac extension and concurrent bilateral multiple pulmonary nodules: a report of 2 cases. [ncbi.nlm.nih.gov]

Baltimore), № 100 https://doi.org/10.1097/MD.0000000000024228 Zhang, Intravenous leiomyomatosis with inferior vena cava or intracardiac extension and concurrent bilateral multiple [ouci.dntb.gov.ua]

Lung Leiomyoma

Our second case was a fifty-six-year-old female who presented with multiple cavitary pulmonary nodules. [scienceopen.com]

This should be considered in the differential in patients who present with multiple pulmonary nodules, especially with a history of uterine leiomyoma. [scienceopen.com]

Pulmonary Meningioma

A pre-operative chest CT scan revealed multiple pulmonary nodules in the superior lobe of the right lung (Fig. 3). [spandidos-publications.com]

PPM should be listed in the differential diagnoses of single or multiple pulmonary nodules, even though it may present as a ground-glass opacity nodule on a CT scan. [hindawi.com]

Cytology of primary pulmonary meningioma. Report of the first multiple case, Acta Cytol, 1998, vol. 42 (pg. 1424 - 1430 ) [10],. [academic.oup.com]

Actinomycetales Infection

As the patient's CECT chest exam revealed extensive pulmonary infiltrates, multiple pulmonary nodules, and loculated pleural effusion, actinomycosis was never a strong suspicion [tandfonline.com]

Stannosis

Differential diagnosis For radiographic appearance of multiple extremely dense nodules, consider: pulmonary alveolar microlithiasis pulmonary baritosis See also pneumoconiosis [pacs.de]

Differential diagnosis For radiographic appearance of multiple extremely dense nodules, consider: pulmonary alveolar microlithiasis pulmonary baritosis See also pneumoconiosis [radiopaedia.org]

[…] hyperdense pulmonary nodules Siehe auch: Pneumonokoniose alveoläre Mikrolithiasis pulmonary baritosis multiple kleine hyperdense Lungenherde und weiter: differential diagnosis [pacs.de]

Pulmonary Candidiasis

Computed tomography scans revealed multiple pulmonary nodules and hilar and mediastinal enlarged lymph nodes. [ncbi.nlm.nih.gov]

Pulmonary cryptococcosis. A Multiple pulmonary subpleural nodules seen at autopsy. [isradiology.org]

Chest radiograph showing multiple pulmonary nodules. [emedicine.medscape.com]

Pulmonary Histiocytosis X

Multiple cavitating pulmonary nodules due to eosinophilic granuloma. [kjim.org]

[…] differential of multiple pulmonary nodules and differential of miliary opacities for more comprehensive lists. [radiopaedia.org]

As pulmonary histiocytosis X progresses, the nodules decrease in number, leaving multiple thin-walled cysts. [ncbi.nlm.nih.gov]

Parasitic Lung Disease

Beryllium-associated lung disease may also present with multiple pulmonary nodules that on imaging may mimic sarcoidosis. [icnet.uk]

Both conditions can develop into ‘progressive massive fibrosis’ (PMF) or multiple pulmonary nodules that range in size from 1 to 10 cm. [icnet.uk]

Caplan’s disease is a combination of rheumatoid arthritis and coal-worker’s pneumoconiosis that manifests with multiple pulmonary nodules. [icnet.uk]

Malignant Neoplasm of the Parathyroid Gland

CT imaging identified no visible disease in the neck but multiple pulmonary nodules consistent with metastatic disease were noted (Figure 2a ). [frontiersin.org]

In a search for distant metastases, the patient underwent pulmonary computerized tomography, and multiple pulmonary nodules were found ( Figure 1 ). [scielo.br]

An abdominal ultrasound showed multiple renal cysts. Nuclear octreotide scintigraphy was completely negative. Figure 2. [frontiersin.org]

Kidney Lipoma

CT chest showed multiple pulmonary nodules bilaterally and a large, expansile lytic lesion of the left scapula, all concerning for metastatic disease. [urologytimes.com]

Light Chain Disease

In all cases there were single or multiple pulmonary nodules, in one case associated with cysts. [jcp.bmj.com]

Kijner CM, Yousem SA: Systemic light chain deposition disease presenting as multiple pulmonary nodules. Am J Surg Pathol, 12: 405–413, 1988. [link.springer.com]

The pulmonary nodules were multiple or unique and varied in size from 0.7–4 cm. [erj.ersjournals.com]

Myopericytoma

Here, we report a case of pulmonary myopericytoma presenting as multiple nodules in a 26-year-old man. [ncbi.nlm.nih.gov]

Xiao-lian Song, Xin-ying Sun, Guo-liang Zhang, Yong-wei Yu and Chang-hui Wang, Myopericytoma Presenting As Multiple Pulmonary Nodules, Internal Medicine, 51, 6, (639), (2012 [doi.org]

Myopericytoma presenting as multiple pulmonary nodules. Intern. Med. 2012;51:639–642. [PubMed] [Google Scholar] 13. Zhang Z., Yu D., Shi H., Xie D. [ncbi.nlm.nih.gov]

Epithelioid Hemangioendothelioma

Imaging revealed bilobar liver lesions consistent with HEHE, a discrete left lobe lesion suspected as HCC, and multiple pulmonary nodules. [ncbi.nlm.nih.gov]

We also estimated overall survival.The most common pattern of thoracic involvement was multiple pulmonary nodules (n = 10), followed by parenchymal tumor with pleural invasion [ncbi.nlm.nih.gov]

Chest computed tomography (CT) performed during a routine cancer screening revealed multiple small pulmonary nodules in a 50-year-old man who had previously undergone endoscopic [ncbi.nlm.nih.gov]

Duodenal Adenocarcinoma

The hypermetabolism was also observed in retroperitoneal para-aortic lymph nodes and multiple pulmonary nodules in both lungs, indicating potential metastasis. [jgo.amegroups.com]

Subarachnoid Abscess

Chest radiograph showed bilateral multiple pulmonary nodules, some of which contained a cavity. Blood culture was positive for Streptococcus constellatus. [ncbi.nlm.nih.gov]