Secondary Amenorrhea: Causes & Reasons

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Possible Causes for Secondary Amenorrhea

Asherman Syndrome

A 27-year-old Zulu woman, para 1, presented with secondary amenorrhea after an uncomplicated cesarean delivery. Hormone levels were in the normal ranges. [ncbi.nlm.nih.gov]

Asherman's syndrome secondary amenorrhea in a hormonally normal woman, caused by obliteration of the endometrial cavity by adhesions that form as a result of curettage, infection [medical-dictionary.thefreedictionary.com]

amenorrhea is typical. [checkorphan.org]

Virilization

A 33-year-old woman presented to an endocrinology clinic with a 5-year history of secondary amenorrhea. 2 years before presentation, she had noticed progressively worsening [ncbi.nlm.nih.gov]

We describe a 14-year-old patient with 1-year secondary amenorrhea, who had an ovarian mature teratoma as a cause of her clinical history. [ncbi.nlm.nih.gov]

A Chinese adolescent girl presented with secondary amenorrhea. During follow-up, she gradually developed Cushingoid features and virilization. [ncbi.nlm.nih.gov]

Hyperprolactinemia

Frequency United States This condition occurs in less than 1% of the general population and in 5-14% of patients presenting with secondary amenorrhea. [3] Approximately 75% [emedicine.com]

In women it is usually associated with galactorrhea and secondary amenorrhea; in men it may be a factor in gynecomastia, decreased libido, and impotence. [medical-dictionary.thefreedictionary.com]

Methods: We retrospectively evaluated our outpatient admission records for PCOS, hirsutism, oligomenorrhea, or secondary amenorrhea. [endocrine-abstracts.org]

Premature Ovarian Failure

Three women at the age of 25, 30 and 32 years presented with 5, 6 and 10 years secondary amenorrhea, respectively. [ncbi.nlm.nih.gov]

[…] of 40 years (secondary amenorrhea). [ncbi.nlm.nih.gov]

These three women who were diagnosed as a case of premature ovarian failure, evidenced by long standing secondary amenorrhea, secondary infertility, signs and symptoms of [ncbi.nlm.nih.gov]

Autoimmune Ovarian Failure

METHOD OF STUDY: The medical history of three young women who presented with secondary amenorrhea following HPV vaccination was collected. [ncbi.nlm.nih.gov]

or premature depletion of ovarian follicles before the age of 40 years (secondary amenorrhea). [ojrd.biomedcentral.com]

[…] or secondary amenorrhea and a subsequent loss of fertility and ovarian hormonal function. [oapublishinglondon.com]

Sheehan Syndrome

A 25-year-old woman presented with lactation failure, secondary amenorrhea, features of hypothyroidism and a hypocortisol state following severe postpartum hemorrhage after [ncbi.nlm.nih.gov]

After this episode she started having acyclic menses, occurring after prolonged periods of time, followed by secondary amenorrhea. [austinpublishinggroup.com]

amenorrhea for many. [omicsonline.org]

Forbes-Albright Syndrome

Moreover, we Distinguish primary amenorrhea, a when at the age of 18 years have not yet Appeared flows menstrual, and secondary amenorrhea, a when you have amenorrhea for [brainscape.com]

Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica. No known specific anesthetic considerations for this syndrome. [accessanesthesiology.mhmedical.com]

Keywords Psychosomatic Medicine Gonadotropin Secretion Regular Menstrual Cycle Health Foundation Secondary Amenorrhea These keywords were added by machine and not by the authors [link.springer.com]

Polycystic Ovary Syndrome

She was advised to visit the endocrinology department for secondary amenorrhea and endocrine survey. [ncbi.nlm.nih.gov]

Patient 4 had prepubertal overgrowth that evolved into pseudo-acromegaly, insulin resistance, secondary amenorrhea, and androgen excess at 15.6 years. [ncbi.nlm.nih.gov]

Symptoms of PCOS include changes in the menstrual cycle, such as: Not getting a period after you have had one or more normal ones during puberty ( secondary amenorrhea ) Irregular [nlm.nih.gov]

Prolactinoma

In women of reproductive age, the symptoms are typically oligomenorrhea or secondary amenorrhea, galactorrhea, and sterility, followed by decreased libido, dry vaginal mucosa [ncbi.nlm.nih.gov]

amenorrhea. [symptoma.com]

Such alterations appear in adolescent females as delayed puberty (48% in our experience), primary amenorrhea (14–41%), secondary amenorrhea (29–45%) and oligomenorrhea (up [karger.com]

Menopause Ovarian Disorder

In secondary amenorrhea, menstruation starts but then stops. [froedtert.com]

Among younger women (aged 30 years or younger) with secondary amenorrhea, 13% also have been noted to have an abnormal karyotype ( 5 ). [acog.org]

Amenorrhea — absence or cessation of menstruation. In primary amenorrhea, menstruation never occurs at puberty. [froedtert.com]

Ovarian Androblastoma

In many cases secondary amenorrhea is the only symptom of the disease. This leads to an intensive search for the source of the disorder. [ncbi.nlm.nih.gov]

The recommendation to include the measurement of androgen levels in the routine diagnosis of secondary amenorrhea must therefore be endorsed. [ncbi.nlm.nih.gov]

Panhypopituitarism

The patient who suffered from secondary amenorrhea was found a nonfunctioning pituitary macroadenoma, and the hormone test showed serum cortisol, FT3, FT4, thyrotropic hormone [ncbi.nlm.nih.gov]

(delayed puberty), secondary amenorrhea, irregular menstrual cycles, infertility Males: delayed puberty, loss of libido, infertility, testicular atrophy, loss of facial, [amboss.com]

Girls may have primary or secondary amenorrhea. Polyuria and polydipsia due to central diabetes insipidus may also be a presenting symptom. [emedicine.medscape.com]

Chronic Alcoholism

ENDOCRINE – Cirrhosis leading to gynecomastia and testicular atrophy, amenorrhea/infertility. Alcohol can also cause hypoglycemia in alcoholics. [errolozdalga.com]

ONCOLOGY – alcohol predisposes to multiple cancers, most notably Hepatocellular carcinoma (secondary to cirrhosis), also ENT and esophageal cancers (synergistic with smoking [errolozdalga.com]

Pituitary Disorder

Clinical Practice Jul 22, 2010 Functional Hypothalamic Amenorrhea Gordon C.M. | N Engl J Med 2010; 363:365-371 A 16-year-old girl presents for evaluation of secondary amenorrhea [nejm.org]

Estrogen deficiency in approximately 50% of premenopausal women with secondary amenorrhea is attributable to acquired gonadotropin-releasing hormone (GnRH) dysregulation, [hindawi.com]

Hyperprolactinemia Hyperprolactinemia causes secondary hypogonadism and may have sex hormone-independent effects on bone metabolism [17, 18]. [hindawi.com]

Ectopic Pregnancy

She had secondary amenorrhea for nine weeks. Transvaginal ultrasonography revealed normal empty uterus and right interstitial ectopic pregnancy with viable embryo. [ncbi.nlm.nih.gov]

Hypothalamic Lesion

Case 2 A 21-year-old woman was referred for secondary amenorrhea. She had been treated for seven years with DDAVP for DI. [em-consulte.com]

Tubal Pregnancy

Secondary amenorrhea varies, as nearly half of women with tubal pregnancies have some spotting at the time of their expected menses and thus do not realize they are pregnant [symptoma.com]

Anorexia Nervosa

Anorexia nervosa Treatment of secondary amenorrhoea and infertility Secondary amenorrhea is a hallmark of anorexia nervosa. [jeatdisord.biomedcentral.com]

Endocrine symptoms in anorexia nervosa include hypothermia (feeling cold), delayed onset of menses or secondary amenorrhea, and osteopenia progressing to osteoporosis. 11, [aafp.org]

Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake. [jeatdisord.biomedcentral.com]

Adrenogenital Syndrome

However, because they do not have female internal reproductive organs, these individuals have amenorrhea and do not develop female secondary sex characteristics. [ncbi.nlm.nih.gov]

Women with complete 17a-hydroxylase/17,20-lyase deficiency do not develop secondary sex characteristics, such as breasts and pubic hair, and do not menstruate (amenorrhea) [ncbi.nlm.nih.gov]

Women with partial 17a-hydroxylase/17,20-lyase deficiency may develop some secondary sex characteristics; menstruation is typically irregular or absent. [ncbi.nlm.nih.gov]

Pituitary Apoplexy

( delayed puberty ), secondary amenorrhea, irregular menstrual cycles, infertility Males: delayed puberty, loss of libido, infertility, testicular atrophy, loss of facial [amboss.com]

[…] include weight gain, weakness, and depression Prolactin deficiency Females: lactation failure following delivery Males: asymptomatic FSH / LH deficiency Females: primary amenorrhea [amboss.com]

Pituitary Cushing Syndrome

“Minnie G.,” as she became historically known, presented with a “… syndrome of painful obesity, hypertrichosis, and amenorrhea with overdevelopment of secondary sexual characteristics [doi.org]

hypertrichosis (abnormal hair growth), underdevelopment of secondary sexual characteristics, hydrocephalus and cerebral tension.[3] This combination of symptoms was not [en.wikipedia.org]

Harvey Cushing in 1912, after he was presented with a unique case of the disease in 1910[23][24] a 23-year-old woman called Minnie G. whose symptoms included painful obesity, amenorrhea [en.wikipedia.org]

Hemochromatosis

Hemochromatosis is the abnormal accumulation of iron in parenchymal organs and the most common form of iron overload disease. It may be inherited or acquired. The patients suffering from hemochromatosis have the following clinical picture. The skin of these patients acquires a bronze pigmentation due to the[…] [symptoma.com]

Hyperthyroidism

Hyperthyroidism usually begins slowly. At first, the symptoms may be mistaken for simple nervousness due to stress. If you have been trying to lose weight by dieting, you may be pleased with your success until the hyperthyroidism, which has quickened the weight loss, causes other problems. In Graves’ disease, which[…] [web.archive.org]

Graves Disease

Graves disease is an autoimmune thyroid disorder characterized by hyperthyroidism, ophthalmopathy and goitre. The autoimmune process in Graves disease is influenced by a combination of environmental and genetic factors. The signs and symptoms of Graves' disease include insomnia, tremor, hyperactivity, hyperhidrosis,[…] [symptoma.com]

Autoimmune Hepatitis

Autoimmune hepatitis Micrograph showing a lymphoplasmacytic interface hepatitis -- the characteristic histomorphologic finding of autoimmune hepatitis. Liver biopsy. H&E stain. Specialty Gastroenterology, hepatology Autoimmune hepatitis, formerly called lupoid hepatitis, is a chronic, autoimmune disease of the liver that[…] [en.wikipedia.org]

Adrenal Cortex Hormone

Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700].DB09124MedrogestoneA progestin used as an adjunct to control secondary amenorrhea [drugbank.ca]

Hypogonadism and amenorrhea can also be seen in these patients which are attributed to suppression of gonadotropin secretion secondary to excess glucocorticoid secretion [ [intechopen.com]

amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.DB00396ProgesteroneA [drugbank.ca]

Myxedema

Myxedema coma occurs as a result of long-standing, undiagnosed, or undertreated hypothyroidism and is usually precipitated by a systemic illness. Myxedema coma can result from any of the causes of hypothyroidism, most commonly chronic autoimmune thyroiditis. It can also occur in patients who had thyroidectomy or[…] [emedicine.com]

Pituitary Neoplasm

Pituitary neoplasms are benign adenomas in the vast majority of cases and can secrete pituitary hormones such as prolactin and growth hormone. Symptoms include a headache and bitemporal hemianopsia in larger tumors, while hormone-induced effects such as acromegaly, galactorrhea, and Cushing's disease may be[…] [symptoma.com]

Achard Thiers Syndrome

A clinical and metabolic study of 20 cases Original Contributions 142 Downloads 1 Citations Summary Twenty patients, selected on the basis of simultaneous existence of overt diabetes and marked hirsutism, were submitted to clinical and biological investigations. Obesity, hypertension and angiopathy were present in most[…] [dx.doi.org]

Abdominal Pregnancy

Abstract Abdominal gestation is a relatively uncommon complication of pregnancy. Previous reports describe a high incidence of fetal deformations and mortality as well as maternal mortality. A case of twin abdominal gestation is presented and the literature concerning abdominal pregnancy since 1809 is reviewed. The[…] [doi.org]