Presentation
[…] in the sixth decade ( Adv Anat Pathol 1999;6:317 ) Sites Nasal cavity, maxillary antrum and ethmoid sinus are typically involved, either alone or in combination Usually presents as an extensively infiltrative disease involving multiple sites, including [pathologyoutlines.com]
Clinical presentation depends greatly on the central tumoral focus and on its invasive components. [radiopaedia.org]
Case presentation A 56-year-old female of Mediterranean descent presented with a 1 year history of swelling on the left side of her nose, nasal obstruction and occasional minor epistaxes. [ncbi.nlm.nih.gov]
In the present case, the metastatic tumor invades the nasal vestibule, vault and ala, with repeated episodes of hemorrhage. [omicsonline.org]
A 50-year-old male patient presented to our Plastic and Reconstructive Surgery Department for nodulo-ulcerative lesions on the nose, developed on scarred tissue surrounded by skin desquamation without well defined margins. [medichub.ro]
Entire Body System
- Weight Loss
This can make it hard to eat, which can lead to weight loss and weakness from poor nutrition. Some people may need to adjust what they eat during and after treatment. [cancer.org]
Skin
- Ulcer
Red arrow – ulcerated lesion. Blue arrow – ipsilateral nasal ala retraction After a thorough assessment of the tumor’s size, shape, location and extension, we decided to perform the surgery under general anaesthesia. [medichub.ro]
The tumor predominantly invaded the subepithelial stroma with mucosal ulceration and hemorrhage. Occasional vascular space permeation was noticed as well. [omicsonline.org]
In our case, there was no ulceration of the overlying squamous epithelium and the patient presented with swelling on the left side of her nose, nasal obstruction and occasional minor epistaxes. [ncbi.nlm.nih.gov]
Treatment
If cancer does come back (recur), treatment will depend on the location of the cancer and what treatments you’ve had before. [cancer.org]
And they can give you treatment suited to your own particular needs. [cancerresearchuk.org]
We consider the case presented to be illustrative of how treatment options should be judged. We support tumor biopsy before taking any decision because histological high-risk features can definitely guide us towards the correct treatment option. [medichub.ro]
Encouraging experience in the treatment of nasal type extra-nodal NK/T-cell lymphoma in a non-Asian population. Leuk Lymphoma. 2018;57:2575-2583. 7. Yamaguchi M, Tobinai K, Oguchi M, et al. [cancertherapyadvisor.com]
A nasal tear may also result from a type of breast cancer treatment called bevacizumab plus chemotherapy. Nonsurgical Treatments In some cases, you might get a tear during or after nose surgery, especially surgery to fix a crooked septum. [webmd.com]
Prognosis
Treatment and prognosis These tumors are generally locally invasive, with a high tendency to recur. [radiopaedia.org]
The clinicians and the pathologists should always be aware of such unusual presentation owing to the poor prognosis and the possibility of rapid deterioration. [omicsonline.org]
[…] usually develop over a relatively short duration (weeks to months) This is a characteristic, though not pathognomonic feature of SNUC Radiology images Images hosted on other servers: Site of SNUC Prognostic factors SNUC is a highly aggressive neoplasm Prognosis [pathologyoutlines.com]
Radiotherapy and PGEMOX/GELOX regimen improved prognosis in elderly patients with early-stage extranodal NK/T-cell lymphoma. Ann Hematol. 2015;94(9):1525-1533. 13. Huang MJ, Jiang Y, Liu WP, et al. [cancertherapyadvisor.com]
Greater than 2 cm tumor, the invasion of the skin, cartilage, bone, or lips represent poor prognosis 13. Nasal region tumors have the most common recurrence and metastasis rate among cancers originating from the mid-fascial area 6. [firattipdergisi.com]
Epidemiology
Definition / general Rare, highly aggressive and clinicopathologically distinct malignancy of uncertain histogenesis Terminology Sinonasal undifferentiated carcinoma (SNUC) Undifferentiated (anaplastic) carcinoma Epidemiology Rare tumor, 85% smokers More [pathologyoutlines.com]
Epidemiology of cancer of the nose and paranasal sinuses: current concepts. Head Neck Surg. 1979; 2 :3–11. doi: 10.1002/hed.2890020103. [ PubMed ] [ CrossRef ] [ Google Scholar ] 30. Halperin EC, Perez CA, Brady LW, editors. [ncbi.nlm.nih.gov]
Pathophysiology
Pathology and pathophysiology of AIDS and HIV-related diseases. St Louis: C. V. Mosby; 1989. pp. 83–134. [ Google Scholar ] 36. La Ferla L, Pinzone MR, Nunnari G, et al. Kaposi’s sarcoma in HIV-positive patients: the state of art in the HAART-era. [ncbi.nlm.nih.gov]
Prevention
Using a humidifier may help moisten your breathing passages, improve the flow of mucus from your sinuses, and help prevent blockages and inflammation. Clean the humidifier daily to prevent bacteria from growing. Use a nasal rinse. [mayoclinic.org]
Your doctor will give you a list of important things to avoid as you recover, such as: decongestant nasal sprays and pills medication containing caffeine smoking and smoke-filled rooms Follow all your doctor’s advice to prevent the hole from opening up [webmd.com]
Full-thickness defects of the nasal ala require cartilage graft in order to prevent alar collapse during inhaling. Cartilage grafts require strong vascular support offered only by flaps. [medichub.ro]
Local treatment modalities are useful for cosmesis or the management of symptomatic bulky KS lesions, but they do not prevent the development of new lesions in untreated areas. [ncbi.nlm.nih.gov]