Presentation
Purely IPNETs are tumors presenting mainly in children and young adults (age from 3 months to 29 years; mean 12.9 years). There are not evident sex differences (ratio female: male 1.25: 1). [scielo.isciii.es]
Treatment
At seven reported cases of purely IPNETs in which chemotherapy or a combination of radiotherapy and chemotherapy were administered either as primary treatment or as treatment after progression, recurrence or intracranial dissemination, temporary clinical [scielo.isciii.es]
Seven patients died of treatment-related toxicities (20%). Thirteen (37%) are event-free survivors at a median post-ASCR follow-up of 18 months (range: 5–63 months). [analesdepediatria.org]
Prognosis
Medulloblastoma and other primary malignant neuroectodermal tumor of the CNS: The effect of age and the patients extent of disease on prognosis. J Neurosurg, 57 (1982), pp. 446-451 [17.] E.L. Kaplan, P. Meier. [analesdepediatria.org]