Presentation
The histologic findings of HSV, when present, are pathognomonic. [archivesofpathology.org]
We are currently sequencing the full genome of HHV-4 present in human saliva using both Roche 454 and Illumina sequencing technology. [sanger.ac.uk]
METHODS: Aqueous humor samples were collected from 42 patients suspected of having AU of infectious origin at presentation. [ncbi.nlm.nih.gov]
Diagnostic probability increased to >20% if at least three of these predictors were present. [doi.org]
Entire Body System
- Pain
and American Society of Regional Anesthesia and Pain Medicine Disclosure: Nothing to disclose. [medscape.com]
These include: 1. vesicular (small blister) skin lesions at or near the site of injury. 2. localized neurological symptoms such as pain, numbness or itching near the wound site. 3. flu-like aches and pains 4. fever and chills 5. headaches lasting more [web.archive.org]
HHV-1 Herpes simplex 1 HSV-1 Herpes, cold sores, fever blisters Painful groups of vesicles Yes Yes HHV-2 Herpes simplex 2 HSV-2 Herpes, cold sores, fever blisters Painful groups of vesicles Yes Yes HHV-3 Varicella-Zoster VZV Varicella, Chicken pox Scattered [ojcpcd.com]
Shingles is the manifestation of VZV reactivation and although rarely a life-threatening disease, it is perhaps of more concern communitywide because of the pain, not only of the acute lesion but also of the frequent post-herpetic neuralgia, which can [creative-biolabs.com]
The pain and cutaneous signs generally resolve 7 to 10 days after the initial symptoms; however, postherpetic neuralgia is a common complication. [archivesofpathology.org]
- Falling
It most often develops in the spring and the fall, and seems to favor adolescents and young adults. Pityriasis rosea is uncommon in those over 60 years old. It may last months longer when it occurs in this age group. [aocd.org]
The tortoises died either during the spring (April-June: n = 8) or the fall (October-December: n = 4) including also Z02/1970 that was euthanized because of very poor prognosis. [doi.org]
First, we identified individuals with full-length iciHHV-6B or DR-only genomes that fall into the same clade in the phylogenetic tree (Figure 3). [elifesciences.org]
- Varicella-Zoster Virus Infection
Complement-fixing reactivity of Varicella-Zoster virus subunit antigens with sera from homotypic infections and heterotypic Herpes simplex virus infections. Infect Immun. 1977 Mar;15(3):850–854. [ncbi.nlm.nih.gov]
Virus et peau. Paris: Esterm; 1994: 17–20. Google Scholar Straus SE, Ostrove JM, Inchauspe G et al. NIH conference. Varicella-zoster virus infections. Biology, natural history, treatment, and prevention. Ann Intern Med 1988; 108:221–237. [link.springer.com]
Science. (1990) [ Pubmed ] Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread. Li, Q., Ali, M.A., Cohen, J.I. [wikigenes.org]
Gastrointestinal
- Diarrhea
Pestiviruses Pestiviruses account for important diseases in animals such as Classical swine fever (CSF) and Bovine viral diarrhea / Mucosal disease (BVD/MD). [horizonpress.com]
Uncommon symptoms (cough, diarrhea) were also present, but in most patients, it related to concomitant infections. Lymphomonocytosis ≥50% of the WBC was the only IM laboratory feature frequently observed. [doi.org]
- Abdominal Pain
Other variable symptoms include lymphadenitis and lymphangitis, nausea and vomiting, abdominal pain, and hiccups ( 12, 14 ). [doi.org]
Skin
- Skin Lesion
If you have a specific question or concern about a skin lesion or disease, please consult a dermatologist. [aocd.org]
These include: 1. vesicular (small blister) skin lesions at or near the site of injury. 2. localized neurological symptoms such as pain, numbness or itching near the wound site. 3. flu-like aches and pains 4. fever and chills 5. headaches lasting more [web.archive.org]
Ancient Greeks—Hippocrates have the name herpes to a mysterious disease that caused “creeping” skin lesions. [humansandviruses.wordpress.com]
The term herpes is derived from the Greek word “to creep or crawl” and dates back to early Greek civilization, approximately 2000 years ago, in reference to the spreading nature of herpetic skin lesions. Herpes simplex virus type 1. [emedicine.medscape.com]
- Eczema
Often, the herald patch is mistaken for ringworm ( tinea corporis ) or eczema. Within a week or two more pink patches will occur on the body and on the arms and legs. [aocd.org]
One of the most important steps in determing the cause of the creeping lesions occurred in 1884 when American doctor Louis Duhring differentiated them from eczema and pemphigus, which are not contagious. [humansandviruses.wordpress.com]
Dis. (2008) [ Pubmed ] Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. [wikigenes.org]
Eyes
- Anterior Uveitis
[…] with HLA B-27 positive anterior uveitis (n=8), Behçet disease (n=6), Fuchs' heterochromic cyclitis (FHC) (n=4), sarcoidosis anterior uveitis (n=1) and multiple sclerosis (MS) related uveitis (n=1). [iovs.arvojournals.org]
PURPOSE: To target the use of two biologic tests in the diagnostic of viral Herpesviridae anterior uveitis (AC) by the consideration of clinical behavior and delay of intraocular sampling. [ncbi.nlm.nih.gov]
Not only anterior uveitis but one related study also revealed a high frequency of positive results without complications from aqueous analysis among patients with posterior uveitis. [dovepress.com]
Urogenital
- Urinary Retention
In our case, despite the administration of empirical antiviral therapy with acyclovir as the first line for viral encephalitis, the patient developed polymyeloradiculopathy consisting of urinary retention, respiratory failure, and flaccid paralysis of [virologyj.biomedcentral.com]
retention.1 Herpes simplex virus 2 has been recently linked with the recurrence of atypical genital symptoms such as vulvar burning and itching, skin fissures, erythema, and repeat menstrual cycles with white vaginal discharge, often mistaken by the [archivesofpathology.org]
Neurologic
- Meningism
Key words: aseptic meningitis, lymphocytic meningitis, lymphomonocytary meningitis, cerebrospinal fluid, central nervous system, enterovirus, herpesvirus. [scielo.br]
[…] involvement (meningoencephalitis), 70% mortality rate if left untreated; causes about 2% of acute pharyngotonsillitis; Classic presentation of a primary HSV-2 infection is herpes genitalis, HSV 2 – genital herpes, sexually transmitted, associated with aseptic meningitis [ehs.stanford.edu]
Herpes simplex virus type 2 and acute aseptic meningitis. Clinical features of cases with isolation of herpes simplex virus from cerebrospinal fluids. Scand J Infect Dis. 1975. 7(4):227-32. [Medline]. [emedicine.medscape.com]
- Headache
These include: 1. vesicular (small blister) skin lesions at or near the site of injury. 2. localized neurological symptoms such as pain, numbness or itching near the wound site. 3. flu-like aches and pains 4. fever and chills 5. headaches lasting more [web.archive.org]
[…] and Pain Management, Jersey Institute of Neuroscience Manish K Singh, MD is a member of the following medical societies: American Academy of Neurology, American Academy of Pain Medicine, American Association of Physicians of Indian Origin, American Headache [medscape.com]
= 72) and per disease * All IM‐like syndromes ( n = 72) Primary CMV infections ( n = 36) Primary Toxoplasma gondii infections ( n = 16) Primary EBV infections ( n = 15) Primary HIV infections ( n = 5) Symptoms and signs Fever >7 days 72 74 69 80 60 Headache [doi.org]
Case presentation A 26-year-old immunocompetent male presented with dizziness, blurred vision, a 3-day history of fever, frontal headache, cervical and lumbar pain, and vomiting during the last 24 h. [virologyj.biomedcentral.com]
Inclusion criteria CSF samples were included in the study based on the clinical criteria of meningitis: acute onset (<3 weeks), presence of fever (>38ºC), meningo-radicular signs and headache. [scielo.br]
- Dizziness
Case presentation A 26-year-old immunocompetent male presented with dizziness, blurred vision, a 3-day history of fever, frontal headache, cervical and lumbar pain, and vomiting during the last 24 h. [virologyj.biomedcentral.com]
Workup
Therefore, combination of classic predictors is necessary to increase substantially the posttest probability of a first‐line workup. Precise etiologic diagnosis requires serological testing against all four commonly associated pathogens. [doi.org]
Microbiology
- Toxoplasma Gondii
“While previous studies have focused on the effect of individual infectious exposure, namely, Herpesviridae viruses or Toxoplasma gondii (T gondii), on cognitive functioning, the objective of the present study was to examine the effect of multiple infections [psychcongress.com]
While previous studies have focused on the effect of individual infectious exposure, namely, Herpesviridae viruses or Toxoplasma gondii (T gondii), on cognitive functioning, the objective of the present study was to examine the effect of multiple infections [ncbi.nlm.nih.gov]
Abstract Background Infectious mononucleosis (IM), resulting from Epstein–Barr virus (EBV) infection, and IM‐like syndromes, mainly due to cytomegalovirus (CMV), Toxoplasma gondii, or human immunodeficiency virus (HIV), have been occasionally reported [doi.org]
Treatment
Treatment with cmvIL-10 reduced TNF-α levels by 86%. Unexpectedly, treatment with JAK1 inhibitor did not cause TNF-α levels to rise significantly. [doi.org]
Treatment: DHPG [9-(l,3-dihydroxy-2-propoxymethy)guanine] is an effective antiviral agent that suppresses CMV during treatment, but does not eradicate it. [link.springer.com]
For mild cases, no treatment is required as this disease is not a dangerous skin condition. [aocd.org]
HSV as a Treatment Vector for Cancer HSV has been an object of interest into research and development as a treatment vector for cancer. [microbewiki.kenyon.edu]
Prognosis
Advances in the technology available for the diagnosis of B virus infection and in the agents for its treatment are improving the prognosis for cases in human beings. [doi.org]
In these patients, prognosis is probably driven more by the underlying condition (namely, ARDS and other organ failures) than by HSV or CMV reactivation. [annalsofintensivecare.springeropen.com]
The tortoises died either during the spring (April-June: n = 8) or the fall (October-December: n = 4) including also Z02/1970 that was euthanized because of very poor prognosis. [dx.plos.org]
Etiology
CONCLUSIONS: While the GWC is progressively less often performed, these findings suggest that it still has a role in AU suspected of herpesvirus etiology. [ncbi.nlm.nih.gov]
There is little information on the etiology of viral meningitis in Brazil especially in the Southern region. [scielo.br]
Consequently, a single herpesvirus species can be attributed to a wide range of diseases as etiological agents or cofactors. [intechopen.com]
Clinical recognition of symptoms and appropriate advanced testing are necessary to correctly identify the infectious etiology. [journals.lww.com]
Epidemiology
Unfortunately, the epidemiology of B virus in group-housed macaques is poorly understood. [doi.org]
For each viral pathogen, we will describe the epidemiology, natural history, screening and diagnosis modalities, treatments, and implications for antepartum care. [journals.lww.com]
The findings of the present study have contributed to a better understanding of the epidemiology of these viruses in this region. [scielo.br]
Pathophysiology
The pathophysiology, epidemiology, clinical presentations of disease, diagnostic investigations, imaging characteristics, and treatment for each infectious etiology are discussed in detail. Author Information Address correspondence to Dr Kelly J. [journals.lww.com]
Biology and Pathophysiology The Herpesviridae family includes viruses that infect animals and humans (Siakallis 2009). Among these viruses, eight members are known to infect humans and are clinically important (Siakallis 2009). [lifeextension.com]
The current hypothesis concerning pathophysiology is that chronic alveolar epithelial cell injury leads to an aberrant reparative response resulting in chronic architecture remodelling of the lung. [openres.ersjournals.com]
HSV infection is mediated through attachment via ubiquitous receptors to cells, including sensory neurons, leading to establishment of latency. [1] Pathophysiology HSV-1 and HSV-2 are characterized by the following unique biological properties: [1] Neurovirulence [emedicine.medscape.com]
Prevention
Article Navigation 1 Department of Epidemiology, Emory University, and Centers for Disease Control and Prevention, Atlanta, Georgia 2 Centers for Disease Control and Prevention, Atlanta, Georgia Reprints or correspondence: Stephanie A. S. [doi.org]
Alternatively, vaccine in those with latent HSV could prevent reactivation, recurrent disease, and transmission. Clinical HSV vaccine trials should define clearly the types of protection being measured. [creative-biolabs.com]
Concept for Epstein-Barr virus infection treatment and prevention Cytomegalovirus CMV, a DNA virus from Herpesviridae family. 3D illustration. [shutterstock.com]
Prevention and Control: Infection can be prevented by avoiding close personal contact (including sexual) with an actively infected individual. [link.springer.com]