Presentation
We presented dichotomous outcomes as RRs with 95% CIs using a fixed‐effect model. [cochranelibrary.com]
Entire Body System
- Fever
Parsons 2016 conducted a systematic review of nine randomised placebo‐controlled trials in which hypertensive patients with mean age ≥ 65 years received antihypertensive or control treatment for a minimum duration of 2 years (FEVER 2011; HYVET 2008; MRC‐O [cochranelibrary.com]
- Congestive Heart Failure
The cardiovascular mortality and morbidity outcome in HYVET P 2003 includes fatal and non‐fatal stroke, fatal MI, other fatal ischaemic heart disease, sudden death, fatal congestive heart failure, fatal atherosclerosis, fatal pulmonary embolism, fatal [cochranelibrary.com]
Cardiovascular
- Vascular Disease
Data for those 60 and over with hypertension at baseline were not available HOPE‐HYP 2000 Double‐blind RCT in patients 55 years or older with previous coronary artery disease, cerebrovascular disease, or peripheral vascular disease or diabetes plus one [cochranelibrary.com]
- Heart Failure
Uncontrolled high blood pressure can lead to heart attack, stroke, aneurysm (life‐threatening if ruptured), heart failure, kidney damage, and vision loss (due to thickened, damaged, or torn blood vessels in the eye). [cochranelibrary.com]
- Hypertension
Mean blood pressure at entry in the three isolated systolic hypertension trials was 172/81 mmHg. Two studies recruited persons with isolated systolic hypertension, diastolic hypertension, or systo‐diastolic hypertension (Carter 1970; Coope 1986). [cochranelibrary.com]
Workup
Hypertrophy
- Ventricular Hypertrophy
Older people also accumulate higher rates of other risk factors for cardiovascular disease such as obesity, left ventricular hypertrophy, sedentary lifestyle, hyperlipidaemia, and diabetes. [cochranelibrary.com]
Treatment
Randomised patients who started treatment in the control group or stopped treatment in the treatment group were still analysed in the treatment group to which they were originally randomised. [cochranelibrary.com]
Prevention
Evidence of benefit pertains mostly to a primary prevention population and to first‐line treatment with a thiazide. [cochranelibrary.com]