Presentation
A single lesion or multiple lesions (lentigines) may be present at birth or more commonly first develop in early childhood. [medicine.academic.ru]
In both conditions, an increased number of pigment-producing cells (melanocytes) is present. Lentigo simplex can occur anywhere on the body, including areas that are not exposed to sunlight. [skinsight.com]
Ink-spot lentigo limited also to sun-exposed areas of the body, the most common presentation includes one ink-spot among an extensive number of solar lentigines. [dermpathdiagnostics.com]
Entire Body System
- Pain
Advanced Search: • Use “ “ for phrases o [ “pediatric abdominal pain” ] • Use – to remove results with certain terms o [ “abdominal pain” –pediatric ] • Use OR to account for alternate terms o [teenager OR adolescent ] [msdmanuals.com]
Foci of darkly pigmented mucosa (lower left portion of image) in the proximal and mid-esophagus, an incidental finding in an 82 year-old man undergoing endoscopy for evaluation of abdominal pain. [endoatlas.com]
The spots don’t cause pain or itchiness and are benign, meaning that they don’t develop into skin cancer. [healthline.com]
not painful or itchy Lentigo simplex lesions are distinguished from freckles by their darker colour, comparative sparseness and scattered distribution. They also do not darken or increase in number on sun exposure, as do freckles. [dermnetnz.org]
- Pathologist
The pathologist examines the biopsy under a microscope. [dovemed.com]
This is where a piece of skin is removed under local anaesthesic and sent for analysis by a pathologist. Treatments for lentigines Most lentigines are left alone, unless there is uncertainty around the diagnosis or an unusual appearance. [myskindoctor.co.uk]
This kind of restriction should be considered by clinicians and pathologists while dealing with such small lesions. REFERENCES 1 Tran KT, Wright NA, Cockerell CJ. Biopsy of the pigmented lesion--when and how. [scielo.br]
- Fever
Symptoms include intense itching, stinging and pain, and in severe allergic contact dermatitis fever. Acute skin lesions present as well demarcated erythema and edema. Small papules and vesicles, bullae, and confluent erosions may also develop. [intechopen.com]
Skin
- Freckles
not painful or itchy Lentigo simplex lesions are distinguished from freckles by their darker colour, comparative sparseness and scattered distribution. They also do not darken or increase in number on sun exposure, as do freckles. [dermnetnz.org]
Lentigo and Freckles (Ephelides) is a topic covered in the 5-Minute Clinical Consult. [unboundmedicine.com]
- Hyperpigmentation
Pallister–Killian syndrome Periorbital hyperpigmentation Photoleukomelanodermatitis of Kobori Postinflammatory hyperpigmentation Transient neonatal pustular melanosis Other pigments Iron Hemochromatosis Iron metallic discoloration Pigmented purpuric [zims-en.kiwix.campusafrica.gos.orange.com]
Integument: Mostly occurring in plural, pinhead- to lentil-sized, brown, sharply defined hyperpigmentations. Preference for light-exposed areas of skin. A transition into a melanocytic nevus is possible. [altmeyers.org]
Microscopy There is variable basal hyperpigmentation with an increased number of single melanocytes in the basal layer. There is usually acanthosis, with regular elongation of the rete ridges. [humpath.com]
ICD-10-CM Codes › L00-L99 Diseases of the skin and subcutaneous tissue › L80-L99 Other disorders of the skin and subcutaneous tissue › L81- Other disorders of pigmentation › Other melanin hyperpigmentation 2016 2017 2018 2019 2020 Billable/Specific Code [icd10data.com]
- Skin Lesion
General Gross Microscopic Sign out Left Hand Lesion, Radial, Biopsy: - Simple lentigo/early seborrheic keratosis. Block letters SKIN LESION, LEFT ABDOMEN, BIOPSY: - SIMPLE LENTIGO, COMPLETELY EXCISED IN THE PLANE OF SECTION. [librepathology.org]
Lentigo simplex is an extremely common, benign melanocytic skin lesion, which can be regarded as the precursor lesion of acquired junctional melanocytic nevus, nowadays called Clark nevus. [dermoscopy.org]
Lentigo simplex is a benign form of pigmented skin lesion. Developing in childhood or early adulthood, lesions are 1-2mm macules that are well circumscribed. Colour is tan to brown. [gpnotebook.co.uk]
Last reviewed 01/2018 Lentigo simplex is a benign form of pigmented skin lesion. Developing in childhood or early adulthood, lesions are 1-2mm macules that are well circumscribed. Colour is tan to brown. [gpnotebook.com]
A single lesion or multiple lesions (lentigines) may be present at birth or more commonly first develop in early childhood. [medicine.academic.ru]
- Keratosis
"A comparison of dermoscopic features among lentigo senilis/initial seborrheic keratosis, seborrheic keratosis, lentigo maligna and lentigo maligna melanoma on the face.". J Dermatol 31 (11): 884-9. PMID 15729860. ↑ Busam, Klaus J. (2009). [librepathology.org]
[…] palmoplantaris, palmoplantar keratoderma + Ectodermal dysplasia + Psoriasis + Psoriatic erytroderma + Palmoplantar psoriasis and palmoplantar pustulosis + Generalized pustular psoriasis of Zumbusch + Lingua geographica + Psoriatiform keratosis + Infantile [atlases.muni.cz]
Differential Diagnosis (Other conditions with similar appearance) Actinic Keratosis Ephelides (Freckles) Seborrheic Keratosis Melanoma Lentigo Maligna Melanoma Diagnosis Key Points *Diagnosis based on appearance of the affected area *Skin biopsy and other [ozarkderm.com]
Lentigo maligna melanoma: clusters of MelanA+ cells at dermoepidermal junction, versus scattered for solar lentigo (J Cutan Pathol 2008;35:931) Macular seborrheic keratosis: thicker lesion, horn cysts / pseudocytes and on continuum with solar lentigo [pathologyoutlines.com]
- Lentigo Senilis
"A comparison of dermoscopic features among lentigo senilis/initial seborrheic keratosis, seborrheic keratosis, lentigo maligna and lentigo maligna melanoma on the face.". J Dermatol 31 (11): 884-9. PMID 15729860. ↑ Busam, Klaus J. (2009). [librepathology.org]
Lentigo senilis — Klassifikation nach ICD 10 L81.4 Lentigo … Deutsch Wikipedia Lentigo solaris — Klassifikation nach ICD 10 L81.4 Lentigo … Deutsch Wikipedia Lentigo — Klassifikation nach ICD 10 L81.4 Lentigo … Deutsch Wikipedia Lentigo maligna — Die [medicine.academic.ru]
Not uniformly defined and used (clinical and histological) term for a usually 0.1-0.3 cm large, but also larger (up to 3.0 cm), acquired (e.g. due to actinic influences = lentigo solaris = lentigo senilis), seasonally non-reversible, brown pigment spot [altmeyers.org]
Workup
Workup Dermoscopic evaluation of a few lichenoid regressing solar lentigines showed a pattern similar to that of lichenoid regressing seborrheic keratosis. [3] Preferentially expressed antigen in melanoma immunostaining may be utilized to distinguish [emedicine.medscape.com]
Treatment
Treatment *Does not typically require treatment *Sunscreens may be used to prevent further development *May be permanently removed, if the affected person desires OTC Options: Sunscreen Lentigines do not typically require treatment, as lesions are benign [ozarkderm.com]
One to two treatments will be necessary. There are many non-laser treatment approaches to treat such spots. [dermcoll.edu.au]
Peitsch Published online: 14 Jul 2015 Favourite Read & Respond COMMENTARIES BRAF in early stage melanoma: rationale for testing and treatment? Authors: M.A. Davies Published online: 14 Jul 2015 Favourite Read & Respond [bjdonline.com]
Prognosis
Thicker melanomas at discovery or those with regional lymph node metastasis have a poorer prognosis; and patients with disseminated disease at time of diagnosis have a bleak prognosis. [intechopen.com]
When treatment is required but cannot be provided within primary care - eg, treatment with local chemical peel or lasers (Q-switched Nd:YAG or ruby) are effective when available. [ 8, 9 ] Prognosis Lentigines tend to worsen over time but do not become [patient.info]
Prognosis Lentigines are benign by nature. In patients in whom lentigines are associated with systemic abnormalities or complications, the prognosis may depend on the severity of the associated conditions. [emedicine.medscape.com]
Keywords: Diagnosis; Melanoma; Nevi and melanomas; Pathology INTRODUCTION Early detection of malignant melanoma (MM) is critical for a good prognosis and its eventual cure. [scielo.br]
Etiology
The etiology of melanoma is unknown. [intechopen.com]
Epidemiology Frequency yet to be determined Etiology Present at birth or more commonly first develop in early childhood; not induced by sun or associated with any medical diseases Pathogenesis Only a few develop initially, but over time up until adult [dermpathdiagnostics.com]
(Etiology) The cause of development of Lentigo Simplex is unknown. [dovemed.com]
Etiology and Pathophysiology Ephelides occur as a result of increased melanin content inside of keratinocytes, mainly seen in the basal cell layer. The number of melanocytes is normal. [unboundmedicine.com]
Multiple clinical and etiologic varieties exist. The distinction of a lentigo from other melanocytic lesions (eg, melanocytic nevi, melanoma) and its role as a marker for ultraviolet damage and systemic syndromes is of major significance. [emedicine.medscape.com]
Epidemiology
Terminology Also called solar lentigines, age spots Epidemiology Sun exposed skin of elderly (90% of whites age 60+); also truck drivers on sun exposed face (J Dermatol 2008;35:146) Multiple large solar lentigos on upper back and shoulders suggest prior [pathologyoutlines.com]
Epidemiology and Etiology : The lesions are hereditary, occurring more commonly and more extensively in males, and they do not appear until after age 30. [intechopen.com]
Epidemiology Frequency yet to be determined Etiology Present at birth or more commonly first develop in early childhood; not induced by sun or associated with any medical diseases Pathogenesis Only a few develop initially, but over time up until adult [dermpathdiagnostics.com]
Epidemiology Incidence The incidence of ephelides, solar lentigines, and simple lentigines is currently unknown, with limited information on these benign entities reported in the literature. [unboundmedicine.com]
Radiation lentigo is caused by local high-dose irradiation. [15] Epidemiology Frequency United States In America, solar lentigines are observed in as many as 90% of whites older than 60 years and in 20% of whites younger than 35 years. [emedicine.medscape.com]
Pathophysiology
Etiology and Pathophysiology Ephelides occur as a result of increased melanin content inside of keratinocytes, mainly seen in the basal cell layer. The number of melanocytes is normal. [unboundmedicine.com]
Pathophysiology Long-term exposure to ultraviolet radiation and pollution as one ages may induce the common solar lentigo. [5] Depending on the type of lentigo present, a solitary lesion or multiple lesions can occur anywhere on the body. [emedicine.medscape.com]
Prevention
However, use of sunscreen may prevent new lesions from forming and existing lesions from becoming darker in the case of solar lentinges. [ozarkderm.com]
How can lentigines be prevented Lentigines associated with exposure ultraviolet radiation can be prevented by very careful sun protection. Clothing is more successful at preventing new lentigines than are sunscreens. [myskindoctor.co.uk]
Currently, there are no known methods to prevent Lentigo Simplex occurrence. However, some of the risk factors may be recognized and controlled. [dovemed.com]
Prevention [ 1 ] New lesions can be prevented to some extent by sun avoidance. Clothing is more effective than sunscreens. Avoiding the excessive use of sunbeds helps to prevent tanning-bed lentigines. [patient.info]