Presentation
Morbidity was present in 12 (22%) patients (atrial fibrillation and hyperpyrexia) (5) (Table 2). [amj.amegroups.com]
A 51-year-old Caucasian female presented with left pleural carcinosis 9-months after two sequential abdominal surgical procedures combined with HIPEC for low-grade PMP. [europeanreview.org]
Intraoperatively, the entire pleura presented pervaded with a brown affection and was covered with white nodules (Figure 2). [journals.lww.com]
In conclusion, the presented heterogenous cohort demonstrates different important aspects of PIPAC and PITAC. [oatext.com]
Clinical presentation depends on the extent of the effusion, how long it has been developing, and the patent’s overall physical condition (2). [ncbi.nlm.nih.gov]
Entire Body System
- Fever
The most common side effects of the local inflammation reaction to chemical pleurodesis are pain and fever (24). Pain can also be reduced using local application of lidocaine as a sclerosing agent (12). [ncbi.nlm.nih.gov]
- Hyperthermia
Hyperthermia improvs the efficacy of chemotherapy. Ried et al. have shown under ex vivo hyperthermic conditions, that cisplatin penetrates into human lung tissue with a median penetration depth of approximately 3–4 mm (21). [amj.amegroups.com]
Other satellite papers describe the effects on tumor tissues by combining pressurized drug vaporization with hyperthermia [24], electrostatic precipitation [25], irradiation [26-28], nanoparticles [29] or hyperthermal nanoaerosol [30]. [oatext.com]
- Sepsis
[…] chemical toxic reactions, 1 renal failure, 1 severe splanchnic pain) and 6 AEs had an unclear relationship to the chemotherapy (2 air-leakages after PITAC with wedge resection in the same operation, 2 intestinal obstructions, 1 bowel perforation with sepsis [oatext.com]
Respiratoric
- Pleural Effusion
Figure 1 Right-side pleural effusion in a patient with breast cancer Figure 2 Left-side pleural carcinosis with malignant pleural effusion and condition following primary insertion of chest drain Conclusive evidence of a malignant pleural effusion can [aerzteblatt.de]
Right-side pleural effusion in a patient with breast cancer Left-side pleural carcinosis with malignant pleural effusion and condition following primary insertion of chest drain Conclusive evidence of a malignant pleural effusion can only be provided [ncbi.nlm.nih.gov]
- Cough
Clinical symptoms The extent of the effusion is the main responsible for the symptoms and signs, progressive dyspnea, accompanied or not by chest pain, and cough is a common symptom. [amj.amegroups.com]
Psychiatrical
- Suggestibility
This suggests that the overall behavioral pattern of the disease has strong similarities in patients with and without pleural effusion/carcinosis and merits an equally high therapeutic effort approach. [ijgc.bmj.com]
More aggressive surgical therapies such as VATS pleurectomy has not been suggested by several guidelines. [amj.amegroups.com]
In fact, this was just an atypical result obtained retrospectively, though it may be suggested that the critical factor is not the detection method but the amount of effusion or the extent of dissemination. [jto.org]
65.7%) 2+ > Cycles (PIPAC or PITAC) 18 (34.3%) Patients (n=35) n (%) PIPAC only 25 (71,4%) PITAC only 4 (11,4%) PIPAC and PITAC 6 (17.2%) Twenty-three procedures were performed just once per patient and only eighteen could be repeated at a later date, suggesting [oatext.com]
Workup
X-Ray
- Pneumoperitoneum
References Reymond MA, Hu B, Garcia A, Reck T, Köckerling F, et al. (2000) Feasibility of therapeutic pneumoperitoneum in a large animal model using a microvaporisator. Surg Endosc 14: 51-55. [oatext.com]
Pleura
- Pleural Effusion
Figure 1 Right-side pleural effusion in a patient with breast cancer Figure 2 Left-side pleural carcinosis with malignant pleural effusion and condition following primary insertion of chest drain Conclusive evidence of a malignant pleural effusion can [aerzteblatt.de]
Right-side pleural effusion in a patient with breast cancer Left-side pleural carcinosis with malignant pleural effusion and condition following primary insertion of chest drain Conclusive evidence of a malignant pleural effusion can only be provided [ncbi.nlm.nih.gov]
Treatment
Palliative Treatment of Malignant Pleural Effusion Medicine 2015 The pathophysiology of MPE is addressed and the treatment options for patients with MPE are addressed, including palliative treatments to effectively control pleural effusions and relieve [semanticscholar.org]
The treatment is palliative, rather than curative. [ncbi.nlm.nih.gov]
Prognosis
Loddenkemper Medicine Pneumologie 2005 The diagnostic approach, the differential diagnosis including causes of paramalignant effusions, as well as the therapeutic possibilities are described, which will hopefully improve the treatment and prognosis of [semanticscholar.org]
The prognosis of patients with non-small cell lung cancer found to have carcinomatous pleuritis at thoracotomy. Crossref PubMed Scopus (26) Google Scholar, but Fukuse et al. demonstrated that MPE had a better prognosis than MPN. [jto.org]
ICD codes for this diseases: C38.4 Pleural carcinosis cases in Germany Map Recommended specialists Experts by Cities Your Location Pleural carcinosis cases in Germany 1.061 cases in the year 2020 1.058 cases in the year 2023 ( Prognosis ) The predicted [leading-medicine-guide.com]
Malignant pleural effusion is a common evolution of various cancers and is associated with poor prognosis and quality of life. About 28% of patients with primary malignancy will develop pleural metastasis. [clinicaltrials.gov]
The prognosis after the occurrence of the MPE during the EOC in relapsed cases was poor with 9,9 months. [ijgc.bmj.com]
Etiology
Checking the amylase in the pleural effusion can confirm the etiology of such effusion. Portal hypertension of every, even malignant etiology, is a possible cause of pleural effusion. [amj.amegroups.com]
Thoracoscopic talc pleurodesis is recommended mainly for patients with pleural effusion of unclear etiology and intraoperatively-detected pleural carcinosis (13, 16, e23, e24). [ncbi.nlm.nih.gov]
Pathophysiology
Palliative Treatment of Malignant Pleural Effusion Medicine 2015 The pathophysiology of MPE is addressed and the treatment options for patients with MPE are addressed, including palliative treatments to effectively control pleural effusions and relieve [semanticscholar.org]
Table 1 Clinical experience with 23 patients with extrathoracic cancers Metastatic cancer Number (n=23) Breast 9 Thymus 2 Malignant lymphoma 2 Bladder 2 Rhabdomyosarcoma 1 Kidney 1 Larynx 1 Idiopathic 5 Pathophysiology The parietal pleura has a more significant [amj.amegroups.com]
Prevention
Both talc pleurodesis and indwelling pleural catheters have been demonstrated to prevent recurrent effusion and thereby also reduce complaints (18, 28, e21). [ncbi.nlm.nih.gov]