Presentation
There is no vitritis present. Brown et al reported that 88% of patients with PIC had bilateral disease, compared to 66% in MCP, 100% in DSF (diffuse subretinal fibrosis), and 25% in MEWDS patients[8]. [eyewiki.aao.org]
Entire Body System
- Inflammation
Disease Entity ICD9: 363.20 chorioretinitis, unspecified ICD10: H30.9 Chorioretinal inflammation, unspecified ICD10: H30.1 Disseminated chorioretinal inflammation Disease Punctate inner choroidopathy (PIC) is an idiopathic inflammatory disorder of the [eyewiki.aao.org]
Sahel and Martine Mauget-Fa{\"y}sse}, year={2014} } Lappellation "syndromes des taches blanches" (White dot syndromes) designe diverses entites ayant en commun une inflammation choroidienne ou retinienne dont l'origine pourrait etre secondaire a une dysregulation [semanticscholar.org]
Eyes
- Enlarged Blind Spot
Enlarged blind spots in chorioretinal inflammatory disorders. Ophthalmology. 1996;103:606--17 ↑ Watzke RC, Shults WT. Clinical features and natural history of the acute idiopathic enlarged blind spot syndrome. [eyewiki.aao.org]
- Blurred Vision
Symptoms Blurred vision, photopsia, central and/or peripheral scotomatas and metamorphopsias. Studies have reported the commonest reported initial symptoms are unilateral scotoma and blurred vision[9]. [eyewiki.aao.org]
- Scotoma
Visual fields show enlargement of the blind spot in approximately 41% of cases and central and paracentral scotoma. [eyewiki.aao.org]
Skin
- Macula
In many patients the blind spot extended towards the macula and the authors theorized this may have been due to the peripapillary clustering of the inflammatory lesions[13]. [eyewiki.aao.org]
Treatment
Intravitreal bevacizumab and ranibizumab Several case series have reported the successful treatment of CNVM with anti-VEGF treatments[33] [34]. [eyewiki.aao.org]
Prognosis
Prognosis Visual prognosis is good in the absence of CNVM with 50-75% of eyes having visual acuity better than 20/25. [eyewiki.aao.org]
Etiology
Etiology The etiology has remained unclear with a wide spectrum of theories proposed. [eyewiki.aao.org]
Pathophysiology
Pathophysiology There are several theories as to the etiology including those discussed above (eg an inflammatory or infectious thrombosis of the choriocapillaris layer by an unidentified organism), however the specific mechanism remains elusive. [eyewiki.aao.org]
Prevention
Primary prevention There are no known preventive measures for PIC. Diagnosis Diagnosis is based on clinical examination. Ancillary tests from the options below can be used as adjuncts in difficult cases. [eyewiki.aao.org]