Presentation
Besides classic skin lesions, various primary and secondary clinical presentations that can be seen are related to a site of the tumor cell infiltrations. However, B-cell IVL presenting with anasarca edema was not previously reported. [tandfonline.com]
Unfortunately, he did not follow up for refills on his medications, nor did he present for the urgent renal appointment he was referred to. [glomcon.org]
Here, we report the case of a 42-year-old woman presenting with thrombocytopenia, anasarca, inflammatory syndrome, renal insufficiency, reticulin myelofibrosis at bone marrow biopsy and cervical and axillary lymph nodes. [casereports.bmj.com]
Significant perinephric and fascial fluid was present, along with minimal ascites, gallbladder wall oedema, abundant subcutaneous and fascial fluid in the dorsum, consistent with anasarca state. [eurorad.org]
OHSS may present various complications. It results in the accumulation of fluid causing ascites and effusion. [karger.com]
Entire Body System
- Lymphadenopathy
Organomegaly including hepatosplenomegaly and lymphadenopathy is not seen here Back to article page [jmedicalcasereports.biomedcentral.com]
Our patient had axillary and inguinal lymphadenopathy and anasarca. This situation evokes several differential diagnoses. CMV infection could explain diffuse lymphadenopathy but does not usually cause anasarca. Furthermore, CMV viremia was negative. [frontierspartnerships.org]
A plain computed tomography revealed multiple lymphadenopathy. She was admitted to our hospital for further investigation. [bmcnephrol.biomedcentral.com]
Organomegaly (splenomegaly, hepatomegaly, or lymphadenopathy) 2. Extravascular volume overload (peripheral edema, ascites, or pleural effusion) 3. Endocrinopathy (adrenal, thyroida, pituitary, gonadal, parathyroid, pancreatica) 4. [ajkd.org]
Computerized tomography scan showed diffuse superficial and deep lymphadenopathy, pleural effusions, ascites, and massive hepatosplenomegaly (Figure 1). [hindawi.com]
- Weight Loss
Other features that are commonly described include peripheral edema, anasarca, diarrhea, weight loss, finger clubbing, and thrombocytosis. [ajkd.org]
- Anorexia
She also reported dyspnea, chest tightness, anorexia, and asthenia. The blood pressure was normal. Clinical exam also revealed hyperreflexia, hepatosplenomegaly, and diffuse supracentimetric lymph adenopathy. [hindawi.com]
- Sacral Edema
She was pale, with ankle and sacral edema. Cardiovascular examination revealed sinus tachycardia and normal first and second heart sound. Respiratory examination showed bilateral basal rales and decreased air entry at the bases. [karger.com]
- Malaise
[…] name drugs Avoid contrast dyes used for certain medical tests such as MRIs and CT scans, and Don’t drink excessive amounts of alcohol Symptoms HRS has a variety of nonspecific symptoms, including: Fatigue Abdominal pain A general feeling of illness (or malaise [liverfoundation.org]
Skin
- Skin Lesion
Early skin biopsy is important for early diagnosis and to start early treatment. Besides classic skin lesions, various primary and secondary clinical presentations that can be seen are related to a site of the tumor cell infiltrations. [tandfonline.com]
Biopsy of one of the thoracic skin lesions showed a glomeruloid hemangioma. During the patient’s hospitalization, he developed capillary leakage syndrome leading to oliguria and was started on extracorporeal ultrafiltration. [ajkd.org]
She had no superficial lymphadenopathy, joint pain, neurological findings, or skin lesions, and an examination of her heart and lungs was unremarkable. Laboratory findings on admission are shown in Table 1. [bmcnephrol.biomedcentral.com]
- Pruritus
He denies any metallic taste, pruritus, chest pain, nausea, or vomiting. He has had some decreased appetite. BP was severely elevated and he was admitted to the ICU for intensive control of BP. Notably, he also had acute kidney injury. [glomcon.org]
Face, Head & Neck
- Facial Edema
Initial BP 220/160, anasarca, including upper extremity and facial edema. [glomcon.org]
Workup
Complement normal K/L 4.30 (mildly elevated in light of CKD) Kappa 170, Lambda 35 PTH 250 TSH normal Detailed infectious workup negative HepB surface Ag and Ab: negative, core IgM negative, core IgG positive (!) [glomcon.org]
Treatment
(a and b) The patient appearance following the treatment. Figure 5. (a and b) The patient appearance following the treatment. [tandfonline.com]
Treatment Liver transplantation is the best treatment for HRS but may not be an option for people with HRS-1 who are too sick for the operation. [liverfoundation.org]
Home treatments The following home-care tips may also speed the treatment of your anasarca: Keep moving: Exercise can help pump excess fluid back to your heart. [healthline.com]
[…] of Anasarca For your doctor to give you the correct treatment, they must identify the underlying condition and treat it. [webmd.com]
His primary care physician initiated treatment with furosemide and spironolactone, but there was no improvement in the patient’s edema. [ajkd.org]
Prognosis
Prognosis Prognosis of anasarca depends on the underlying etiology. Reversible causes may carry favorable outcomes, whereas irreversible etiologies and malignancies have a poor prognosis. [statpearls.com]
Prognosis of anasarca depends on the underlying etiology. [ncbi.nlm.nih.gov]
Other options for people who are unable to get a transplant or who are awaiting one include: Vasoconstrictive agents to increase blood pressure that is too low Albumin to improve renal function Prognosis for Anyone Living with HRS The prognosis for people [liverfoundation.org]
Renal biopsy is recommended for treatment and prognosis [1-3]. [eurorad.org]
Etiology
It has an acute or subacute onset of unknown etiology, although some pathological features resemble those of multicentric Castleman disease. We here report two cases of TAFRO syndrome. [jstage.jst.go.jp]
It is managed aggressively by intravenous diuretics, vasodilators, and oxygen therapy.[7] Diagnosis The diagnostic study of choice depends upon the underlying etiology. [wikidoc.org]
Objectives: Identify the etiology of anasarca. Review the presentation of a patient with anasarca. [statpearls.com]
Epidemiology
(PMID: 25795336) [9] Kerlin BA, Ayoob R, Smoyer WE (2012) Epidemiology and pathophysiology of nephrotic syndrome-associated thromboembolic disease.. Clin J Am Soc Nephrol 7:513-520. (PMID: 22344511) [eurorad.org]
Epidemiology The epidemiology of anasarca is not studied yet, but it is one of the common complaints among the patients admitted to the hospital. [statpearls.com]
Pathophysiology
This case report underlines the pathophysiological role of tissue edema in the downward spiral of hepato-renal and cardio-renal dysfunction and illustrates that very large volumes of tissue fluid can be safely and effectively removed with continuous renal [pubmed.ncbi.nlm.nih.gov]
(PMID: 25795336) [9] Kerlin BA, Ayoob R, Smoyer WE (2012) Epidemiology and pathophysiology of nephrotic syndrome-associated thromboembolic disease.. Clin J Am Soc Nephrol 7:513-520. (PMID: 22344511) [eurorad.org]
About the pathophysiology of VEGF in TAFRO syndrome, VEGF balance in the glomerulus and perhaps in the peritubular capillary system as well may be critical. Further investigation is needed. [bmcnephrol.biomedcentral.com]
This activity reviews the causes, pathophysiology, presentation of anasarca and stresses the importance of the interprofessional team in its management. Objectives: Identify the etiology of anasarca. [statpearls.com]
Prevention
If you have cirrhosis, the following will be important to prevent HRS: Avoid nonsteroidal anti-inflammatory drugs (NSAIDs). [liverfoundation.org]
Prevention Leg elevation and pneumatic compression stocking to promote venous and lymphatic drainage from lower limbs.[9][10] Edema in lower limbs increases the risk for skin breakouts and, venous ulcers. [wikidoc.org]
Treating problems with the heart, lungs, kidneys, and liver early on is the best chance of preventing and controlling anasarca in many cases. [medicalnewstoday.com]
ISPD peritonitis recommendations: 2016 update on prevention and treatment. Perit Dial Int. 2016 Sep 10;36(5):481-508. [PubMed] [Google Scholar] Wang Q, Shen M, Leng X, Zeng X, Zhang F, Qian J. [medical.advancedresearchpublications.com]
Local skin and wound care of venous ulcers is essential in preventing secondary cellulitis and dermatitis. [statpearls.com]