Presentation
Attias D, Mansencal N, Auvert B, et al: Prevalence, characteristics, and outcomes of patients presenting with cardiogenic unilateral pulmonary edema. [rcseagles.com]
IUGR was present in all ten individuals without definitive molecular diagnosis. [nature.com]
Medicine Annals of Saudi medicine 2004 Three girls of a Saudi Arabian family with pre-natal and post-natal growth retardation, characteristic cranio-facial dysmorphism, proportionate short stature and some of the skeletal anomalies of Seckel syndrome are presented [semanticscholar.org]
Standard Therapies Treatment Medical treatment for Seckel syndrome is based on the specific problems that are present in the affected child. [rarediseases.org]
Gastrointestinal
- Failure to Thrive
Feeding problems ranged from a small appetite (17/40; 43%) to gastroesophageal reflux (15/41; 37%), and failure to thrive (13/41; 32%). Of 41 individuals, 17 (41%) had tube feeding or gastrostomy interventions. [nature.com]
Skin
- Hirsutism
In addition, affected children may have increased body hair (hirsutism). Another possible feature is a single, deep crease across the palms of the hands (single palmar crease). [rarediseases.org]
Treatment
Treatment will depend seen following instrumental delivery and least frequently on the extent and severity of the infection. [rcseagles.com]
The former received growth hormone treatment from the age of 3 years till the age of 9 years. Initially, her growth velocity increased, but the positive effect wore off and the treatment was stopped. [nature.com]
Bongers Medicine Orphanet Journal of Rare Diseases 2015 Management should be directed towards in-depth investigation, treatment and prevention of associated problems, such as growth retardation, feeding problems, hearing loss, luxating patellae, knee [semanticscholar.org]
Standard Therapies Treatment Medical treatment for Seckel syndrome is based on the specific problems that are present in the affected child. [rarediseases.org]
Prevention
Bongers Medicine Orphanet Journal of Rare Diseases 2015 Management should be directed towards in-depth investigation, treatment and prevention of associated problems, such as growth retardation, feeding problems, hearing loss, luxating patellae, knee [semanticscholar.org]
Determining the presence of coagulopathies, and preventions of complications such as vascular erosions, catheter-associated thrombosis, and air embolism, is also important. [rcseagles.com]
[…] patients and their families, the late RJ Gorlin, DL Guernsey, and RM Winter for their contributions, I van Rooij for statistical advice and assistance, C Ockeloen for her help with consenting and the Medical Research Council and Lister Institute for Preventative [nature.com]