Presentation
For both small plaque parapsoriasis and large plaque parapsoriasis, presentation most frequently is in middle age; peak incidence is in the fifth decade of life. [emedicine.medscape.com]
Rome J Morphol Embryol 55(3 Suppl):1085-1092 Belousova IE et al (2008) A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: report of a case and comparative retrospective study of [altmeyers.org]
Treatment
Patients with long-standing parapsoriasis-like lesions resistant to conventional treatment require careful monitoring for the possible development of cutaneous lymphoma. [pubmed.ncbi.nlm.nih.gov]
Large plaque disease is chronic, and treatment is recommended because it may prevent progression to CTCL. [emedicine.medscape.com]
Prognosis
Prognosis Small plaque parapsoriasis may persist in a stable pattern for years to decades and then resolve spontaneously. A small number of cases may progress to mycosis fungoides (MF). Large plaque parapsoriasis remains indolent for many years. [emedicine.medscape.com]
Etiology
El-Darouti et al reported on a 7-year study of a hypopigmented disorder that the researchers believe should be classified as a new variant of parapsoriasis en plaque. [9] No clear etiology for small plaque or large plaque parapsoriasis is known, and no [emedicine.medscape.com]
Epidemiology
In one study, large plaque parapsoriasis has expression of TOX similar to that of mycosis fungoides. [13] Epidemiology There are no accurate statistics on the incidence and frequency of parapsoriasis, but digitate dermatoses may be underreported because [emedicine.medscape.com]
Pathophysiology
Pathophysiology The initiating cause of parapsoriasis is unknown, but the diseases likely represent different stages in a continuum of lymphoproliferative disorders from chronic dermatitis stimulated by activated T cells to frank malignancy of cutaneous [emedicine.medscape.com]
Prevention
Large plaque disease is chronic, and treatment is recommended because it may prevent progression to CTCL. [emedicine.medscape.com]